Douglas W. Laske

Convection-enhanced delivery of macromolecules in the brain.

R. Hunt Bobo, Douglas W. Laske, Aytaç Akbaşak et al. · Proceedings of the National Academy of Sciences · 1994 · 1.4K citations

Pharmacy, Neuroscience, Pharmaceutics +16

Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumors

Douglas W. Laske, Richard J. Youle, Edward H. Oldfield · Nature Medicine · 1997 · 530 citations

Medicine, Neuroscience, Oncology +10

Convection-enhanced distribution of large molecules in gray matter during interstitial drug infusion

Daniel Lieberman, Douglas W. Laske, Paul F. Morrison et al. · Journal of neurosurgery · 1995 · 346 citations

Pharmacy, Neuroscience, Pharmacology +13

High-flow microinfusion: tissue penetration and pharmacodynamics

Paul F. Morrison, Douglas W. Laske, Hunt Bobo et al. · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 1994 · 318 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Safety and Feasibility of Convection-enhanced Delivery of Cotara for the Treatment of Malignant Glioma: Initial Experience in 51 Patients

Sunil J. Patel, William R. Shapiro, Douglas W. Laske et al. · Neurosurgery · 2005 · 167 citations

Pharmacy, Oncology, Pharmacotherapy +17