Psoralen, a mechanism-based inactivator of CYP2B6

Casarett and Doull's toxicology: The basic science of poisons

Morag Cunninghame, Derek Grant · Food and Chemical Toxicology · 1987 · 790 citations

Pharmacy, Pharmacology, Toxicology +11

The Cytochrome P450 2B6 (CYP2B6) Is the Main Catalyst of Efavirenz Primary and Secondary Metabolism: Implication for HIV/AIDS Therapy and Utility of Efavirenz as a Substrate Marker of CYP2B6 Catalytic Activity

Bryan A. Ward, J. Christopher Gorski, David R. Jones et al. · Journal of Pharmacology and Experimental Therapeutics · 2003 · 594 citations

Medicine, Pharmacokinetics, Pharmacology +17

Validation of Bupropion Hydroxylation as a Selective Marker of Human Cytochrome P450 2B6 Catalytic Activity

Stephanie Faucette, Roy L. Hawke, Edward L. LeCluyse et al. · Drug Metabolism and Disposition · 2000 · 356 citations

Medicine, Biochemistry, Pharmacology +17

Inactivation of Cytochrome P450 3A4 by Bergamottin, a Component of Grapefruit Juice

Kan He, K. R. Krishna Iyer, Roger N. Hayes et al. · Chemical Research in Toxicology · 1998 · 312 citations

Medicine, Biochemistry, Pharmacology +17

Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents: Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins

Paul F. Hollenberg, David Edwards, Kan He et al. · UNC Libraries · 2019 · 311 citations · Full text

Agriculture, Pharmacokinetics, Pharmacology +9