Publication | Open Access

Mutation pattern of immunoglobulin transgenes is compatible with a model of somatic hypermutation in which targeting of the mutator is linked to the direction of DNA replication.

Genome InstabilitySomatic VariantSomatic HypermutationMutation PatternNatural SciencesGeneticsMolecular BiologyGenetic EngineeringDna ReplicationMolecular GeneticsMedicineGenome EditingMutagenesisGene Transfer