Antitumor and cytotoxic properties of a humanized antibody specific for the GM3(Neu5Gc) ganglioside

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

Masato Enari, Hideki Sakahira, Hideki Yokoyama et al. · Nature · 1998 · 3.2K citations

Caspase-activated Dnase, Natural Sciences, Apoptosis +8

Humanization of an anti-p185HER2 antibody for human cancer therapy.

Paul Carter, Leonard G. Presta, C Gorman et al. · Proceedings of the National Academy of Sciences · 1992 · 1.9K citations · Full text

Anti-p185her2 Antibody, Tumor Targeting, Immunology +13

An enzyme-release assay for natural cytotoxicity

Carol Korzeniewski, Denis M. Callewaert · Journal of Immunological Methods · 1983 · 1.1K citations

Biochemistry, Medicine, Bioanalysis +6

The Molecular Basis for the Absence ofN-Glycolylneuraminic Acid in Humans

Atsushi Irie, Susumu KOYAMA, Yasunori Kozutsumi et al. · Journal of Biological Chemistry · 1998 · 404 citations · Full text

The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity

Geert Loo, Marjan van Gurp, Ben Depuydt et al. · Cell Death and Differentiation · 2002 · 350 citations · Full text

Biochemistry, Mitochondrial Function, Medicine +13