The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins

Yasunori Kozutsumi, Mark S. Segal, Karl Normington, +2

Nature

Protein SecretionBiochemistryMalfolded ProteinsProtein FoldingEndoplasmic Reticulum Signals +9

Serine Palmitoyltransferase Is the Primary Target of a Sphingosine-like Immunosuppressant, ISP-1/Myriocin

Yurika Miyake, Yasunori Kozutsumi, Satoshi Nakamura, +2

Biochemical and Biophysical Research Communications

Signal TransductionSphingosine-like ImmunosuppressantMedicineImmunosuppressive TherapyImmunology +8

S. cerevisiae encodes an essential protein homologous in sequence and function to mammalian BiP

Karl Normington, Kenji Kohno, Yasunori Kozutsumi, +2

Cell

Protein FunctionMedicineGeneticsNatural SciencesGenomic Mechanism +9

The Molecular Basis for the Absence ofN-Glycolylneuraminic Acid in Humans

Atsushi Irie, Susumu KOYAMA, Yasunori Kozutsumi, +2

Journal of Biological Chemistry

Cholesterol-dependent Formation of GM1 Ganglioside-bound Amyloid β-Protein, an Endogenous Seed for Alzheimer Amyloid

Atsuko Kakio, Sei‐ichi Nishimoto, Katsuhiko Yanagisawa, +2

Journal of Biological Chemistry

Interactions of Amyloid β-Protein with Various Gangliosides in Raft-Like Membranes:  Importance of GM1 Ganglioside-Bound Form as an Endogenous Seed for Alzheimer Amyloid

Atsuko Kakio, Sei‐ichi Nishimoto, Katsuhiko Yanagisawa, +2

Biochemistry

Isolation and characterization of a mannan-binding protein from rabbit serum

Yasunori Kozutsumi, Toshisuke Kawasaki, Ikuo Yamashina

Biochemical and Biophysical Research Communications

Protein ChemistryMannan-binding ProteinProtein FunctionBiochemistryMedicine +8

Hypoxia induces adhesion molecules on cancer cells: A missing link between Warburg effect and induction of selectin-ligand carbohydrates

Tetsufumi Koike, Naoko Kimura, Keiko Miyazaki, +15

Proceedings of the National Academy of Sciences

<i>N</i>-Glycolylneuraminic Acid Deficiency in Mice: Implications for Human Biology and Evolution

Maria Hedlund, Pam Tangvoranuntakul, Hiromu Takematsu, +9

Molecular and Cellular Biology

GlycobiologyImmunologyCancer BiologyEpigeneticsCellular Physiology +16

Germinal Center Marker GL7 Probes Activation-Dependent Repression of <i>N</i> -Glycolylneuraminic Acid, a Sialic Acid Species Involved in the Negative Modulation of B-Cell Activation

Yuko Naito, Hiromu Takematsu, Susumu KOYAMA, +12

Molecular and Cellular Biology