Karl Normington

The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins

Yasunori Kozutsumi, Mark S. Segal, Karl Normington et al. · Nature · 1988 · 1.3K citations

Protein Secretion, Biochemistry, Malfolded Proteins +11

S. cerevisiae encodes an essential protein homologous in sequence and function to mammalian BiP

Karl Normington, Kenji Kohno, Yasunori Kozutsumi et al. · Cell · 1989 · 415 citations

Protein Function, Medicine, Genetics +11

Tissue distribution and kinetic characteristics of rat steroid 5 alpha-reductase isozymes. Evidence for distinct physiological functions.

Karl Normington, David W. Russell · Journal of Biological Chemistry · 1992 · 376 citations · Full text

A 22 bp cis-acting element is necessary and sufficient for the induction of the yeast KAR2 (BiP) gene by unfolded proteins.

Kazutoshi Mori, Andrea J. Sant, Kenji Kohno et al. · The EMBO Journal · 1992 · 372 citations · Full text

Yeast Kar2, Unfolded Proteins, Natural Sciences +10

The Promoter Region of the Yeast <i>KAR2</i> (BiP) Gene Contains a Regulatory Domain that Responds to the Presence of Unfolded Proteins in the Endoplasmic Reticulum

Kenji Kohno, Karl Normington, Joseph Sambrook et al. · Molecular and Cellular Biology · 1993 · 323 citations · Full text

Regulatory Domain, Genetics, Molecular Biology +22