Lithium protects against methamphetamine-induced neurotoxicity in PC12 cells via Akt/GSK3β/mTOR pathway

Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death.

Naoufal Zamzami, Philippe Marchetti, Maria Castedo et al. · The Journal of Experimental Medicine · 1995 · 1.6K citations · Full text

Life Sciences, Biochemistry, Cell Biology +12

TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth

Ken Inoki, Hongjiao Ouyang, Tianqing Zhu et al. · Cell · 2006 · 1.4K citations

Life Sciences, Cell Biology, Molecular Biology +17

Convergent evidence for impaired AKT1-GSK3β signaling in schizophrenia

Effat S. Emamian, Diana Hall, Morris J. Birnbaum et al. · Nature Genetics · 2004 · 920 citations

Medicine, Neurobiology, Neuroscience +14

Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade

Jean‐Martin Beaulieu, Tatyana D. Sotnikova, Wei‐Dong Yao et al. · Proceedings of the National Academy of Sciences · 2004 · 786 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons

E Chalecka-Franaszek, De‐Maw Chuang · Proceedings of the National Academy of Sciences · 1999 · 540 citations

Life Sciences, Neuroscience, Pharmacology +17