ORIGINAL ARTICLE: Activation of TLR3 in the Trophoblast is Associated with Preterm Delivery

Abstract

We report that Poly[I:C] induces preterm delivery via TLR3-dependent manner. Furthermore, we demonstrate that the trophoblast is able to recognize Poly[I:C] through TLR3 and respond to viral infection, modulating the immune system at the feto-maternal interface.