Dimension Therapeutics (United States)

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1.2K

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Cambridge, United States

Dimension Therapeutics (United States) is a company institution in Cambridge, United States known for adenoviral vectors, gene delivery, and viral vector-mediated transgenesis.

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HematologyGene DeliveryAdenoviral VectorsGene TherapyBiotechnologyLife SciencesAdeno-associated Viral VectorsViral Vector-mediated TransgenesisEnhancersPromoters

Publications

Characterization of Adeno-Associated Viral Vector-Mediated Human Factor VIII Gene Therapy in Hemophilia A Mice

Jenny A. Greig, Qiang Wang, Amanda L. Reicherter et al. · Human Gene Therapy · 2017 · 43 citations

Life Sciences, Biotechnology, Hematology +15

Safety and Efficacy of AAV Retrograde Pancreatic Ductal Gene Delivery in Normal and Pancreatic Cancer Mice

Kayla Quirin, Jason J. Kwon, Arafat Alioufi et al. · Molecular Therapy — Methods & Clinical Development · 2017 · 40 citations · Full text

Pharmacy, Biotechnology, Cancer Biology +17

101HEMB01 Is a Phase 1/2 Open-Label, Single Ascending Dose-Finding Trial of DTX101 (AAVrh10FIX) in Patients with Moderate/Severe Hemophilia B That Demonstrated Meaningful but Transient Expression of Human Factor IX (hFIX)

Steven W. Pipe, Kimo C. Stine, Anita Rajasekhar et al. · Blood · 2017 · 30 citations

Medicine, Hematology, Pharmacotherapy +10

Impact of intravenous infusion time on AAV8 vector pharmacokinetics, safety, and liver transduction in cynomolgus macaques

Jenny A. Greig, Jayme M.L. Nordin, Erin Bote et al. · Molecular Therapy — Methods & Clinical Development · 2016 · 17 citations · Full text

Life Sciences, Pharmacokinetics, Pharmacology +16

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Authors

AA
Arafat Alioufi
Dimension Therapeutics (United States), United States
2 publications · 40 citations
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