SiteOne Therapeutics (United States)

1-(1-Acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia

Sampath‐Kumar Anandan, Heather K. Webb, Dawn Chen et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 72 citations · Full text

Medicinal Chemistry, Oxysterol, Biochemistry +7

Discovery of a selective, state-independent inhibitor of NaV1.7 by modification of guanidinium toxins

Hassan Pajouhesh, Jacob T. Beckley, Anton Delwig et al. · Scientific Reports · 2020 · 40 citations · Full text

Antinociceptive properties of an isoform-selective inhibitor of Nav1.7 derived from saxitoxin in mouse models of pain

Jacob T. Beckley, Hassan Pajouhesh, George Luu et al. · Pain · 2020 · 36 citations · Full text

Exploration of secondary and tertiary pharmacophores in unsymmetrical N,N′-diaryl urea inhibitors of soluble epoxide hydrolase

Sampath‐Kumar Anandan, Richard D. Gless · Bioorganic & Medicinal Chemistry Letters · 2010 · 22 citations · Full text

Soluble Epoxide Hydrolase, Medicinal Chemistry, Biochemistry +9

Hair Methylmercury Levels in U.S. Women

Jeremy C. Smith, Paul V. Allen, R. von Burg · Archives of Environmental Health An International Journal · 1997 · 22 citations