DNAtrix (United States)

Oncolytic DNX-2401 Virus for Pediatric Diffuse Intrinsic Pontine Glioma

Jaime Gállego Pérez‐Larraya, Marc García-Moure, Sara Labiano et al. · New England Journal of Medicine · 2022 · 243 citations · Full text

Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial

Farshad Nassiri, Vikas Patil, Leeor Yefet et al. · Nature Medicine · 2023 · 232 citations · Full text

Toca 511 gene transfer and treatment with the prodrug, 5-fluorocytosine, promotes durable antitumor immunity in a mouse glioma model

Leah Mitchell, Fernando Lopez Espinoza, Daniel Mendoza et al. · Neuro-Oncology · 2017 · 94 citations · Full text

DNX-2401, an Oncolytic Virus, for the Treatment of Newly Diagnosed Diffuse Intrinsic Pontine Gliomas: A Case Report

Sonia Tejada, Ricardo Díez-Valle, Pablo Domínguez et al. · Frontiers in Oncology · 2018 · 53 citations · Full text

Pediatric Brain Tumors, Immunology, Pathology +19

Phase 1b open-label randomized study of the oncolytic adenovirus DNX-2401 administered with or without interferon gamma for recurrent glioblastoma.

Frederick F. Lang, Nam Tran, Vinay K. Puduvalli et al. · Journal of Clinical Oncology · 2017 · 41 citations

Oncolytic Adenovirus Dnx-2401, Immunology, Immunoediting +20