Fernando Lopez Espinoza

Toca 511 gene transfer and treatment with the prodrug, 5-fluorocytosine, promotes durable antitumor immunity in a mouse glioma model

Leah Mitchell, Fernando Lopez Espinoza, Daniel Mendoza et al. · Neuro-Oncology · 2017 · 94 citations · Full text

Intravenous Administration of Retroviral Replicating Vector, Toca 511, Demonstrates Therapeutic Efficacy in Orthotopic Immune-Competent Mouse Glioma Model

Tiffany Huang, Shraddha Parab, Ryan Burnett et al. · Human Gene Therapy · 2014 · 64 citations · Full text

Intravenous Administration, Immunology, Immunoediting +16

Toca 511 gene transfer and 5-fluorocytosine in combination with temozolomide demonstrates synergistic therapeutic efficacy in a temozolomide-sensitive glioblastoma model

Tiffany Huang, Juraj Hlavatý, Derek Ostertag et al. · Cancer Gene Therapy · 2013 · 53 citations

Neuro-oncology, Medicine, Temozolomide-sensitive Glioblastoma Model +10

A Retroviral Replicating Vector Encoding Cytosine Deaminase and 5-FC Induces Immune Memory in Metastatic Colorectal Cancer Models

Kader Yagiz, Maria E. Rodriguez-Aguirre, Fernando Lopez Espinoza et al. · Molecular Therapy — Oncolytics · 2017 · 34 citations · Full text

Toca 511 plus 5-fluorocytosine in combination with lomustine shows chemotoxic and immunotherapeutic activity with no additive toxicity in rodent glioblastoma models

Kader Yagiz, Tiffany Huang, Fernando Lopez Espinoza et al. · Neuro-Oncology · 2016 · 23 citations · Full text