Concepedia
Statistics
Publications
6
Citations
900
Location
Wellesley, United States
Janus Biotherapeutics (United States) is a company institution in Wellesley, United States known for pharmacology, t cell responses to tumors, and translation from preclinical to clinical models.
Top concepts
PharmacologyMedicineOncologyPharmacodynamicsT Cell ExpansionReceptor ModelingTumor Cell DepletionImmune Cell DepletionPharmacokinetic ModelingCytokine Release Dynamics
Development of a quantitative relationship between CAR-affinity, antigen abundance, tumor cell depletion and CAR-T cell expansion using a multiscale systems PK-PD model
Aman P. Singh, Xirong Zheng, Xiefan Lin‐Schmidt et al. · mAbs · 2019 · 113 citations · Full text
Medicine, Oncology, Pharmacology +17
Absorption, Distribution, Metabolism, and Excretion of Therapeutic Proteins: Current Industry Practices and Future Perspectives
Jayaprakasam Bolleddula, Kevin Brady, Gerard Bruin et al. · Drug Metabolism and Disposition · 2022 · 49 citations
Pharmacy, Pharmacokinetics, Pharmacology +13
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