Kevin Brady

A long-lived IL-2 mutein that selectively activates and expands regulatory T cells as a therapy for autoimmune disease

Laurence B. Peterson, Sarah Howlett, Marcin Ł. Pękalski et al. · Journal of Autoimmunity · 2018 · 140 citations · Full text

Delivery of the Brainshuttle™ amyloid-beta antibody fusion trontinemab to non-human primate brain and projected efficacious dose regimens in humans

Hans Peter Grimm, Vanessa Schumacher, Martin Schäfer et al. · mAbs · 2023 · 133 citations · Full text

Brain Shuttle Antibody for Alzheimer’s Disease with Attenuated Peripheral Effector Function due to an Inverted Binding Mode

Felix Weber, Bernd Bohrmann, Jens Niewoehner et al. · Cell Reports · 2018 · 99 citations · Full text

Uptake, Efficacy, and Systemic Distribution of Naked, Inhaled Short Interfering RNA (siRNA) and Locked Nucleic Acid (LNA) Antisense

Sterghios Moschos, Manfred Frick, B Keith Taylor et al. · Molecular Therapy · 2011 · 83 citations · Full text

A Slow Clearing, Fibrin-Specific, PAI-1 Resistant Variant of t-PA (T103N, KHRR 296-299 AAAA)

Nicholas F. Paoni, Bruce A. Keyt, Canio J. Refino et al. · Thrombosis and Haemostasis · 1993 · 69 citations · Full text

T-pa Variant, Khrr 296-299, Protein Function +15