Tartis (United States)

p53 cooperates with DNA methylation and a suicidal interferon response to maintain epigenetic silencing of repeats and noncoding RNAs

Katerina I. Leonova, Leonid Brodsky, Brittany C. Lipchick et al. · Proceedings of the National Academy of Sciences · 2012 · 267 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

BMAL1-dependent regulation of the mTOR signaling pathway delays aging

Rohini V. Khapre, Anna A. Kondratova, Sonal A. Patel et al. · Aging · 2014 · 213 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Rapamycin extends lifespan and delays tumorigenesis in heterozygous p53+/− mice

Elena A. Komarova, Marina P. Antoch, Liliya R. Novototskaya et al. · Aging · 2012 · 151 citations · Full text

Education, Oncology, Pharmacology +17

New nanoformulation of rapamycin Rapatar extends lifespan in homozygous p53−/− mice by delaying carcinogenesis

Maria Comas, Ilia Toshkov, Karen K. Kuropatwinski et al. · Aging · 2012 · 116 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4)

Leanna Cheung, Claudia L. Flemming, Fujiko Watt et al. · Biochemical Pharmacology · 2014 · 70 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8