Tartis (United States)

p53 cooperates with DNA methylation and a suicidal interferon response to maintain epigenetic silencing of repeats and noncoding RNAs

Katerina I. Leonova, Leonid Brodsky, Brittany C. Lipchick et al. · Proceedings of the National Academy of Sciences · 2012 · 260 citations · Full text

BMAL1-dependent regulation of the mTOR signaling pathway delays aging

Rohini V. Khapre, Anna A. Kondratova, Sonal A. Patel et al. · Aging · 2014 · 211 citations · Full text

Aging, Mtorc1 Inhibitor Rapamycin, Bmal1-dependent Regulation +16

Rapamycin extends lifespan and delays tumorigenesis in heterozygous p53+/− mice

Elena A. Komarova, Marina P. Antoch, Liliya R. Novototskaya et al. · Aging · 2012 · 149 citations · Full text

Cell Death, Pathology, Mtor Pathway +17

New nanoformulation of rapamycin Rapatar extends lifespan in homozygous p53−/− mice by delaying carcinogenesis

Maria Comas, Ilia Toshkov, Karen K. Kuropatwinski et al. · Aging · 2012 · 116 citations · Full text

High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4)

Leanna Cheung, Claudia L. Flemming, Fujiko Watt et al. · Biochemical Pharmacology · 2014 · 69 citations · Full text

Drug Target, Ceefourin 2, Biochemistry +10