BioZyme (United States)

Species Specificity of ADAM10 and ADAM17 Proteins in Interleukin-6 (IL-6) Trans-signaling and Novel Role of ADAM10 in Inducible IL-6 Receptor Shedding

Christoph Garbers, Nathalie Jänner, Athena Chalaris et al. · Journal of Biological Chemistry · 2011 · 194 citations · Full text

Innate Immune System, Immunology, Cell Death +17

The ADAM10 Prodomain Is a Specific Inhibitor of ADAM10 Proteolytic Activity and Inhibits Cellular Shedding Events

Marcia L. Moss, Martha G. Bomar, Qian Liu et al. · Journal of Biological Chemistry · 2007 · 146 citations · Full text

Specific Inhibitor, Immunology, Proteasome +16

Ectodomain Shedding of the Neural Recognition Molecule CHL1 by the Metalloprotease-disintegrin ADAM8 Promotes Neurite Outgrowth and Suppresses Neuronal Cell Death

Silvia Naus, Melanie Richter, Dirk Wildeboer et al. · Journal of Biological Chemistry · 2004 · 127 citations · Full text

ADAM8 as a drug target in pancreatic cancer

Uwe Schlomann, Garrit Koller, Catharina Conrad et al. · Nature Communications · 2015 · 123 citations · Full text

Fluorescent substrates for the proteinases ADAM17, ADAM10, ADAM8, and ADAM12 useful for high-throughput inhibitor screening

Marcia L. Moss, Fred Rasmussen · Analytical Biochemistry · 2007 · 119 citations

Protein Function, High-throughput Inhibitor Screening, Biochemistry +7