Santhera Pharmaceuticals (Switzerland)

A randomized placebo-controlled trial of idebenone in Leber’s hereditary optic neuropathy

Thomas Klopstock, Patrick Yu‐Wai‐Man, Konstantinos Dimitriadis et al. · Brain · 2011 · 533 citations · Full text

A Phase 3, Double-blind, Placebo-Controlled Trial of Idebenone in Friedreich Ataxia

David R. Lynch, Susan Perlman, Thomas Meier · Archives of Neurology · 2010 · 220 citations · Full text

NQO1-Dependent Redox Cycling of Idebenone: Effects on Cellular Redox Potential and Energy Levels

Roman H. Haefeli, Michael A. Erb, Anja C. Gemperli et al. · PLoS ONE · 2011 · 187 citations · Full text

Lipid Peroxidation, Molecular Biology, Chemical Biology +21

Efficacy of idebenone on respiratory function in patients with Duchenne muscular dystrophy not using glucocorticoids (DELOS): a double-blind randomised placebo-controlled phase 3 trial

Gunnar Buyse, Thomas Voït, Ulrike Schara et al. · The Lancet · 2015 · 182 citations · Full text

Placebo-controlled Phase 3, Respiratory Function, Exercise +4

Discovery of Riociguat (BAY 63‐2521): A Potent, Oral Stimulator of Soluble Guanylate Cyclase for the Treatment of Pulmonary Hypertension

Joachim Mittendorf, Stefan Weigand, Cristina Alonso‐Alija et al. · ChemMedChem · 2009 · 180 citations

Molecular Pharmacology, Pulmonary Arterial Hypertension, Biochemistry +14