Aronora (United States)

Factor XII inhibition reduces thrombus formation in a primate thrombosis model

Anton Matafonov, Philberta Y. Leung, Adam E. Gailani et al. · Blood · 2014 · 215 citations · Full text

The contact activation inhibitor AB023 in heparin-free hemodialysis: results of a randomized phase 2 clinical trial

Christina U. Lorentz, Erik I. Tucker, Norah G. Verbout et al. · Blood · 2021 · 112 citations · Full text

Inhibition of factor XI activation attenuates inflammation and coagulopathy while improving the survival of mouse polymicrobial sepsis

Erik I. Tucker, Norah G. Verbout, Philberta Y. Leung et al. · Blood · 2012 · 102 citations · Full text

Contact Activation Inhibitor and Factor XI Antibody, AB023, Produces Safe, Dose-Dependent Anticoagulation in a Phase 1 First-In-Human Trial

Christina U. Lorentz, Norah G. Verbout, Michael Wallisch et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2019 · 98 citations · Full text

Immunohematology, Immunology, Pharmacotherapy +20

Factor XII promotes blood coagulation independent of factor XI in the presence of long‐chain polyphosphates

Cristina Puy, Erik I. Tucker, Zoë C. Wong et al. · Journal of Thrombosis and Haemostasis · 2013 · 88 citations · Full text

Thrombosis, Factor Xi, Immunology +10