Abcombi Biosciences (United States)

p16(Ink4a) and senescence-associated β-galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli

Brandon M. Hall, Vitaly Balan, Anatoli S. Gleiberman et al. · Aging · 2017 · 374 citations · Full text

Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells

Brandon M. Hall, Vitaly Balan, Anatoli S. Gleiberman et al. · Aging · 2016 · 330 citations · Full text

Aging, Bright Luminescence, Immunology +27

Cells exhibiting strong <i>p16</i> ^<i>INK4a</i> promoter activation in vivo display features of senescence

Jie‐Yu Liu, George P. Souroullas, Brian O. Diekman et al. · Proceedings of the National Academy of Sciences · 2019 · 295 citations · Full text

Senescent cells expose and secrete an oxidized form of membrane-bound vimentin as revealed by a natural polyreactive antibody

David Frescas, Christelle M. Roux, Semra Aygun‐Sunar et al. · Proceedings of the National Academy of Sciences · 2017 · 131 citations · Full text

Physiological frailty index (PFI): quantitative in-life estimate of individual biological age in mice

Marina P. Antoch, Michelle Wrobel, Karen K. Kuropatwinski et al. · Aging · 2017 · 72 citations · Full text