Concepedia

Yeast Reverse Genetics

Yeast Reverse Genetics is a molecular biology approach that involves the targeted disruption or modification of a known yeast gene sequence to determine its functional role in cellular processes, distinguishing it from forward genetics by starting with a defined genetic element rather than an observed phenotype.

31

Publications

2.4K

Citations

164

Authors

77

Institutions

Publications per year

2017–2026

7

Parents

Publications

31

Reverse two-hybrid and one-hybrid systems to detect dissociation of protein-protein and DNA-protein interactions.

Marc Vidal, R. Brachmann, Ali Fattaey et al. · Proceedings of the National Academy of Sciences · 1996 · 430 citations · Full text

, , +14

A Yeast Synthetic Network for In Vivo Assessment of Reverse-Engineering and Modeling Approaches

Irene Cantone, Lucia Marucci, Francesco Iorio et al. · Cell · 2009 · 385 citations · Full text

, , +16

A novel engineered meganuclease induces homologous recombination in yeast and mammalian cells

Jean Charles Epinat · Nucleic Acids Research · 2003 · 261 citations · Full text

, , +12

Identification of revertants for the cystic fibrosis ΔF508 mutation using STE6-CFTR chimeras in yeast

John L. Teem, Herbert A. Berger, Lynda S. Ostedgaard et al. · Cell · 1993 · 183 citations

, , +9

Genetic characterization of a mammalian protein-protein interaction domain by using a yeast reverse two-hybrid system.

Marc Vidal, Ella Chen, Jef D. Boeke et al. · Proceedings of the National Academy of Sciences · 1996 · 172 citations

, , +15

1–5 of 31

Authors

164

  1. WH
    Wei-Chin Ho

    University of Michigan, United States

    2 publications · 97 citations

    2

    h-index

  2. MV
    Marc Vidal

    Dana-Farber Cancer Institute, United States

    2 publications · 602 citations

    2

    h-index

  3. JZ
    Jianzhi Zhang

    University of Michigan, United States

    2 publications · 97 citations

    2

    h-index

  4. EH
    Ed Harlow

    Massachusetts General Hospital, United States

    2 publications · 602 citations

    2

    h-index

  5. JD
    Jef D. Boeke

    Johns Hopkins University, United States

    2 publications · 602 citations

    2

    h-index

1–5 of 164

Institutions

77

  1. Chinese Academy of Sciences

    Beijing, China

    2 h-index

    10 publications

    756 citations

  2. University of Michigan

    Ann Arbor, United States

    2 h-index

    8 publications

    390 citations

  3. Massachusetts General Hospital

    Boston, United States

    2 h-index

    10 publications

    3K citations

  4. Charles University

    Prague, Czechia

    2 h-index

    6 publications

    146 citations

  5. Chinese Academy of Agricultural Sciences

    Beijing, China

    2 h-index

    6 publications

    122 citations

  6. Harbin Veterinary Research Institute

    Harbin, China

    2 h-index

    5 publications

    107 citations

  7. University of Chinese Academy of Sciences

    Beijing, China

    2 h-index

    15 publications

    1.8K citations

  8. Rutgers, The State University of New Jersey

    New Brunswick, United States

    2 h-index

    3 publications

    186 citations

1–8 of 77

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 718 citations

    3

    h-index

  2. Cell

    2 publications · 568 citations

    2

    h-index

  3. Molecular Biology and Evolution

    MBE · 2 publications · 97 citations

    2

    h-index

  4. The Plant Health Instructor

    1 publications · 24 citations

    1

    h-index

  5. Molecular and Cellular Biology

    MCB · 1 publications · 11 citations

    1

    h-index

1–5