Concepedia

Yeast Display Selection

Yeast Display Selection is a laboratory technique in antibody fragment engineering that involves the surface presentation of recombinant antibody fragments on yeast cells, followed by fluorescence-activated cell sorting to isolate variants with desired binding properties based on their displayed phenotype.

37

Publications

2.2K

Citations

214

Authors

95

Institutions

Publications per year

2017–2026

12

Parents

Publications

37

An improved yeast transformation method for the generation of very large human antibody libraries

Lorenzo Benatuil, Jennifer M. Perez, Jonathan Belk et al. · Protein Engineering Design and Selection · 2010 · 465 citations

, , +17

<i>In vitro</i> evolution of a T cell receptor with high affinity for peptide/MHC

Phillip D. Holler, Philmore O. Holman, Eric V. Shusta et al. · Proceedings of the National Academy of Sciences · 2000 · 295 citations · Full text

, , +17

Fine Epitope Mapping of anti-Epidermal Growth Factor Receptor Antibodies Through Random Mutagenesis and Yeast Surface Display

Jennifer R. Cochran, K. Dane Wittrup · Journal of Molecular Biology · 2004 · 132 citations

, , +14

Development of a Human Light Chain Variable Domain (VL) Intracellular Antibody Specific for the Amino Terminus of Huntingtin via Yeast Surface Display

David W. Colby, Payal Garg, Tina Holden et al. · Journal of Molecular Biology · 2004 · 118 citations

, , +15

Protein Engineering and Selection Using Yeast Surface Display

Alessandro Angelini, Tiffany F. Chen, Seymour de Picciotto et al. · Methods in molecular biology · 2015 · 108 citations

, , +12

1–5 of 37

Authors

214

  1. KD
    K. Dane Wittrup

    Massachusetts Institute of Technology, United States

    6 publications · 841 citations

    6

    h-index

  2. MU
    Mitsuyoshi Ueda

    Kyoto University, Japan

    3 publications · 53 citations

    3

    h-index

  3. AB
    Andrew Bradbury

    Los Alamos National Laboratory, United States

    3 publications · 75 citations

    3

    h-index

  4. BJ
    Benjamin J. Hackel

    University of Minnesota, United States

    3 publications · 167 citations

    3

    h-index

  5. JR
    Jennifer R. Cochran

    Stanford University, United States

    2 publications · 224 citations

    2

    h-index

1–5 of 214

Institutions

95

  1. Massachusetts Institute of Technology

    Cambridge, United States

    7 h-index

    30 publications

    3.4K citations

  2. Kyoto University

    Kyoto, Japan

    3 h-index

    7 publications

    107 citations

  3. Los Alamos National Laboratory

    Los Alamos, United States

    3 h-index

    10 publications

    253 citations

  4. Novartis (Switzerland)

    Basel, Switzerland

    2 h-index

    4 publications

    80 citations

  5. Pfizer (United States)

    New York, United States

    2 h-index

    21 publications

    348 citations

  6. Fujifilm (Japan)

    Tokyo, Japan

    2 h-index

    2 publications

    30 citations

  7. University of Illinois Urbana-Champaign

    Urbana, United States

    2 h-index

    10 publications

    1.9K citations

  8. University of Minnesota

    Minneapolis, United States

    2 h-index

    13 publications

    472 citations

1–8 of 95

Venues

  1. Protein Engineering Design and Selection

    PEDS · 8 publications · 672 citations

    8

    h-index

  2. Methods in molecular biology

    Book series · 5 publications · 160 citations

    5

    h-index

  3. Nature Communications

    3 publications · 129 citations

    3

    h-index

  4. Applied Microbiology and Biotechnology

    2 publications · 35 citations

    2

    h-index

  5. Journal of Molecular Biology

    JMB · 2 publications · 250 citations

    2

    h-index

1–5