Concepedia

Yeast Display Libraries

Yeast Display Libraries is a type of recombinant antibody display library that utilizes yeast surface expression systems to link genotype and phenotype by displaying antibody fragments on the yeast cell surface while retaining the corresponding DNA sequence intracellularly for subsequent selection and amplification.

62

Publications

3.7K

Citations

479

Authors

125

Institutions

Publications per year

2017–2026

30

Variants

Yeast Surface Display Libraries

Parents

Publications

62

Flow-cytometric isolation of human antibodies from a nonimmune Saccharomyces cerevisiae surface display library

Michael J. Feldhaus, Robert W. Siegel, Lee K. Opresko et al. · Nature Biotechnology · 2003 · 521 citations

, , +14

An improved yeast transformation method for the generation of very large human antibody libraries

Lorenzo Benatuil, Jennifer M. Perez, Jonathan Belk et al. · Protein Engineering Design and Selection · 2010 · 465 citations

, , +17

Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes

Marvin H. Gee, Arnold Han, Shane Lofgren et al. · Cell · 2017 · 286 citations · Full text

, , +17

Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM

Tomasz Uchański, Simonas Masiulis, Baptiste Fischer et al. · Nature Methods · 2021 · 153 citations · Full text

, , +17

Directed evolution of an anti-carcinoembryonic antigen scFv with a 4-day monovalent dissociation half-time at 37 C

Christilyn Graff, Kerry Chester, Rhj Begent et al. · Protein Engineering Design and Selection · 2004 · 139 citations · Full text

, , +17

1–5 of 62

Authors

479

  1. KD
    K. Dane Wittrup

    Massachusetts Institute of Technology, United States

    6 publications · 924 citations

    6

    h-index

  2. HK
    Harald Kolmar

    Technische Universität Darmstadt, Germany

    5 publications · 146 citations

    5

    h-index

  3. JG
    Julius Grzeschik

    Technische Universität Darmstadt, Germany

    5 publications · 146 citations

    5

    h-index

  4. SZ
    Stefan Zielonka

    Technische Universität Darmstadt, Germany

    4 publications · 126 citations

    4

    h-index

  5. BM
    Balaji M. Rao

    North Carolina State University, United States

    4 publications · 147 citations

    4

    h-index

1–5 of 479

Institutions

125

  1. Massachusetts Institute of Technology

    Cambridge, United States

    9 h-index

    31 publications

    5.4K citations

  2. Stanford University

    Stanford, United States

    6 h-index

    37 publications

    5.5K citations

  3. Technische Universität Darmstadt

    Darmstadt, Germany

    5 h-index

    27 publications

    762 citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    6 publications

    719 citations

  5. Pacific Northwest National Laboratory

    Richland, United States

    4 h-index

    14 publications

    3.4K citations

  6. Merck KGaA, Darmstadt (Germany)

    Darmstadt, Germany

    3 h-index

    19 publications

    764 citations

  7. Vrije Universiteit Brussel

    Brussels, Belgium

    3 h-index

    19 publications

    1.5K citations

  8. University of Wisconsin–Madison

    Madison, United States

    3 h-index

    12 publications

    286 citations

1–8 of 125

Venues

  1. Protein Engineering Design and Selection

    PEDS · 8 publications · 821 citations

    8

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 4 publications · 170 citations

    4

    h-index

  3. Journal of Biological Chemistry

    JBC · 3 publications · 130 citations

    3

    h-index

  4. Journal of Molecular Biology

    JMB · 3 publications · 167 citations

    3

    h-index

  5. Scientific Reports

    3 publications · 80 citations

    3

    h-index

1–5