Concepedia

Yac Construction

YAC Construction is a molecular cloning technique that involves the assembly of artificial chromosomes in yeast by combining essential chromosomal elements—such as centromeres, telomeres, and replication origins—with exogenous DNA sequences to enable stable maintenance and propagation of large DNA fragments.

330

Publications

17.5K

Citations

1.9K

Authors

426

Institutions

Publications per year

2017–2026

2

Parents

Publications

330

Thermal asymmetric interlaced PCR: automatable amplification and sequencing of insert end fragments from P1 and YAC clones for chromosome walking

Yao-Guang Liu, Robert F. Whittier · Genomics · 1995 · 1.1K citations

, , +9

A novel, rapid method for the isolation of terminal sequences from yeast artificial chromosome (YAC) clones

J. Riley, Rachel Butler, Donald Ogilvie et al. · Nucleic Acids Research · 1990 · 646 citations · Full text

, , +12

YAC complementation shows a requirement for <i>Wt1</i> in the development of epicardium, adrenal gland and throughout nephrogenesis

Adrian W. Moore, Lesley McInnes, Jordan A. Kreidberg et al. · Development · 1999 · 540 citations

, , +17

Assignment of the Vascular Endothelial Growth Factor Gene to Human Chromosome 6p21.3

Valeria Vincenti, C. Cassano, Mariano Rocchi et al. · Circulation · 1996 · 472 citations

, , +12

Construction of YAC–based mammalian artificial chromosomes

Masashi Ikeno, Brenda R. Grimes, Tuneko Okazaki et al. · Nature Biotechnology · 1998 · 419 citations

, , +12

1–5 of 330

Authors

1.9K

  1. HL
    Hans Lehrach

    Max Planck Institute for Molecular Genetics, Germany

    21 publications · 891 citations

    15

    h-index

  2. DL
    Denis Le Paslier

    Fondation Jean Dausset-CEPH, France

    14 publications · 894 citations

    13

    h-index

  3. DS
    David Schlessinger

    National Institute on Aging, United States

    15 publications · 470 citations

    13

    h-index

  4. AP
    Anthony P. Monaco

    Centre for Human Genetics, United Kingdom

    10 publications · 555 citations

    10

    h-index

  5. MD
    Michele D’Urso

    Institute of Genetics and Biophysics, Italy

    10 publications · 340 citations

    10

    h-index

1–5 of 1.9K

Institutions

426

  1. Washington University in St. Louis

    St Louis, United States

    23 h-index

    181 publications

    8.5K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    15 h-index

    92 publications

    4.3K citations

  3. Fondation Jean Dausset-CEPH

    Paris, France

    14 h-index

    86 publications

    5.6K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    14 h-index

    60 publications

    3.1K citations

  5. Baylor College of Medicine

    Houston, United States

    13 h-index

    56 publications

    3K citations

  6. Harvard University

    Cambridge, United States

    13 h-index

    68 publications

    4K citations

  7. The Honourable Society of Lincoln's Inn

    London, United Kingdom

    13 h-index

    79 publications

    2.4K citations

  8. National Institutes of Health

    Bethesda, United States

    12 h-index

    77 publications

    2.9K citations

1–8 of 426

Venues

  1. Genomics

    82 publications · 4.1K citations

    28

    h-index

  2. Human Molecular Genetics

    29 publications · 1.7K citations

    22

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 26 publications · 2.4K citations

    22

    h-index

  4. Genome Research

    GR · 26 publications · 924 citations

    18

    h-index

  5. Nucleic Acids Research

    24 publications · 1.6K citations

    17

    h-index

1–5