Concepedia

Xpg Function

Xpg Function is a molecular mechanism within nucleotide excision repair that belongs to the class of structure-specific endonucleases, distinguished by its role in cleaving the DNA strand on the 3′ side of the damaged site during excision of oligonucleotide fragments.

51

Publications

4.6K

Citations

237

Authors

82

Institutions

Publications per year

2017–2026

7

Variants

Xpg Endonuclease

Parents

Publications

51

XPG endonuclease makes the 3′ incision in human DNA nucleotide excision repair

Anne O’Donovan, Adelina A. Davies, Jonathan G. Moggs et al. · Nature · 1994 · 481 citations

, , +5

Defective Transcription-Coupled Repair of Oxidative Base Damage in Cockayne Syndrome Patients from XP Group G

Priscilla K. Cooper, Thierry Nouspikel, Stuart G. Clarkson et al. · Science · 1997 · 306 citations

, , +16

Base Excision Repair of Oxidative DNA Damage Activated by XPG Protein

Arne Klungland, Matthias Höss, Daniela Gunz et al. · Molecular Cell · 1999 · 287 citations · Full text

, , +14

The DNA Repair Endonuclease XPG Binds to Proliferating Cell Nuclear Antigen (PCNA) and Shares Sequence Elements with the PCNA-binding Regions of FEN-1 and Cyclin-dependent Kinase Inhibitor p21

Ronald K. Gary, Dale L. Ludwig, Helen L. Cornelius et al. · Journal of Biological Chemistry · 1997 · 237 citations · Full text

, , +16

Open complex formation around a lesion during nucleotide excision repair provides a structure for cleavage by human XPG protein

Elizabeth L. Evans, Jane Fellows, Arnold I. Coffer et al. · The EMBO Journal · 1997 · 236 citations · Full text

, , +9

1–5 of 51

Authors

237

  1. SG
    Stuart G. Clarkson

    University of Geneva, Switzerland

    7 publications · 937 citations

    7

    h-index

  2. RD
    Richard D. Wood

    Genesis Foundation, United States

    6 publications · 1.3K citations

    6

    h-index

  3. TN
    Thierry Nouspikel

    University of Geneva, Switzerland

    5 publications · 509 citations

    5

    h-index

  4. FT
    Fabrizio Thorel

    Erasmus University Rotterdam, Netherlands

    5 publications · 337 citations

    5

    h-index

  5. TS
    Tadahiro Shiomi

    The University of Osaka, Japan

    4 publications · 195 citations

    4

    h-index

1–5 of 237

Institutions

82

  1. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    7 h-index

    20 publications

    2.1K citations

  2. University of Geneva

    Geneva, Switzerland

    5 h-index

    9 publications

    1.1K citations

  3. The Honourable Society of Lincoln's Inn

    London, United Kingdom

    4 h-index

    13 publications

    3.4K citations

  4. The University of Osaka

    Osaka, Japan

    4 h-index

    13 publications

    1.6K citations

  5. Institut de génétique et de biologie moléculaire et cellulaire

    Illkirch-Graffenstaden, France

    3 h-index

    11 publications

    1.5K citations

  6. University of Zurich

    Zurich, Switzerland

    3 h-index

    12 publications

    690 citations

  7. Cancer Research UK

    London, United Kingdom

    3 h-index

    11 publications

    2.2K citations

  8. Lawrence Berkeley National Laboratory

    Berkeley, United States

    3 h-index

    18 publications

    1.4K citations

1–8 of 82

Venues

  1. Journal of Biological Chemistry

    JBC · 11 publications · 1.3K citations

    11

    h-index

  2. Nucleic Acids Research

    6 publications · 421 citations

    6

    h-index

  3. Journal of Investigative Dermatology

    JID · 3 publications · 104 citations

    3

    h-index

  4. UNC Libraries

    Repository · 3 publications · 35 citations

    3

    h-index

  5. Molecular and Cellular Biology

    MCB · 3 publications · 236 citations

    3

    h-index

1–5