Concepedia

Ww Domains

WW Domain is a type of protein interaction domain characterized by a conserved double-tryptophan residue motif that mediates specific binding to proline-rich peptide ligands and plays a role in assembling multi-protein complexes involved in cellular signaling and regulation.

574

Publications

49.9K

Citations

2.8K

Authors

755

Institutions

Publications per year

2017–2026

105

Variants

Ww Domain

Parents

Publications

574

Atomic-Level Characterization of the Structural Dynamics of Proteins

David E. Shaw, Paul Maragakis, Kresten Lindorff‐Larsen et al. · Science · 2010 · 1.9K citations

, , +17

The importance of being proline: the interaction of proline‐rich motifs in signaling proteins with their cognate domains

Brian K. Kay, Michael P. Williamson, Marius Sudol · The FASEB Journal · 2000 · 1.2K citations

, , +17

Hippo pathway effector Yap promotes cardiac regeneration

Mei Xin, Yuri Kim, Lillian B. Sutherland et al. · Proceedings of the National Academy of Sciences · 2013 · 898 citations · Full text

, , +17

WW domains of Nedd4 bind to the proline‐rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome.

Olivier Staub, Sascha E. Dho, P Henry et al. · The EMBO Journal · 1996 · 850 citations · Full text

, , +7

Autoinhibition and activation mechanisms of the Wiskott–Aldrich syndrome protein

Annette S. Kim, Lazaros T. Kakalis, Norzehan Abdul-Manan et al. · Nature · 2000 · 748 citations

, , +8

1–5 of 574

Authors

2.8K

  1. MS
    Marius Sudol

    Icahn School of Medicine at Mount Sinai, United States

    45 publications · 7.7K citations

    38

    h-index

  2. MT
    Mark T. Bedford

    The University of Texas MD Anderson Cancer Center, United States

    16 publications · 2K citations

    16

    h-index

  3. JW
    Jeffery W. Kelly

    Scripps Research Institute, United States

    16 publications · 1.8K citations

    16

    h-index

  4. MJ
    María J. Macias

    Institute for Research in Biomedicine, Spain

    14 publications · 1.5K citations

    14

    h-index

  5. DR
    Daniela Rotin

    Hospital for Sick Children, Canada

    13 publications · 2.2K citations

    13

    h-index

1–5 of 2.8K

Institutions

755

  1. Icahn School of Medicine at Mount Sinai

    New York, United States

    29 h-index

    76 publications

    10.8K citations

  2. Harvard University

    Cambridge, United States

    25 h-index

    99 publications

    10.8K citations

  3. Scripps Research Institute

    San Diego, United States

    20 h-index

    57 publications

    5.7K citations

  4. University of Toronto

    Toronto, Canada

    20 h-index

    71 publications

    11.4K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    17 h-index

    46 publications

    7.4K citations

  6. Geisinger Medical Center

    Danville, United States

    14 h-index

    25 publications

    3.1K citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    14 h-index

    66 publications

    3.3K citations

  8. The University of Texas MD Anderson Cancer Center

    Houston, United States

    13 h-index

    37 publications

    3.2K citations

1–8 of 755

Venues

  1. Journal of Biological Chemistry

    JBC · 91 publications · 9.1K citations

    57

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 29 publications · 4.8K citations

    28

    h-index

  3. Biochemistry

    17 publications · 645 citations

    14

    h-index

  4. The Journal of Physical Chemistry B

    14 publications · 812 citations

    13

    h-index

  5. PLoS ONE

    13 publications · 470 citations

    13

    h-index

1–5