Viral Replication Compartments is a specialized subnuclear or cytoplasmic microenvironment induced by DNA viruses during infection that serves as a spatially organized hub for the coordinated synthesis, processing, and assembly of viral genomes and structural components, distinguished from general cellular compartments by its virus-specific recruitment of host and viral factors to enhance replication efficiency and evade immune detection.
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High-level hepatitis B virus replication in transgenic mice
Luca G. Guidotti, B Matzke, Heinz Schaller et al. · Journal of Virology · 1995 · 638 citations · Full text
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Harvard University
Cambridge, United States
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Heidelberg University
Heidelberg, Germany
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188 publications
33.2K citations
Howard Hughes Medical Institute
Chevy Chase, United States
20 h-index
35 publications
3.7K citations
Centre National de la Recherche Scientifique
Paris, France
18 h-index
90 publications
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UConn Health
Farmington, United States
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45 publications
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German Cancer Research Center
Heidelberg, Germany
15 h-index
30 publications
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University of Kentucky
Lexington, United States
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