Concepedia

Vector Persistence

Vector Persistence is a pharmacokinetic parameter that characterizes the duration and stability of vector-mediated transgene expression in target tissues following gene delivery, distinguishing it from transient or short-lived gene transfer outcomes.

50

Publications

4K

Citations

369

Authors

130

Institutions

Publications per year

2017–2026

8

Parents

Publications

50

Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors

Richard O. Snyder, Carol H. Miao, G. Patijn et al. · Nature Genetics · 1997 · 585 citations

, , +13

Persistence in muscle of an adenoviral vector that lacks all viral genes

Hsiao‐Huei Chen, Lisa M. Mack, Robert G. Kelly et al. · Proceedings of the National Academy of Sciences · 1997 · 294 citations

, , +16

Sustained AAV-mediated Dystrophin Expression in a Canine Model of Duchenne Muscular Dystrophy with a Brief Course of Immunosuppression

Zejing Wang, Christian S. Kuhr, James M. Allen et al. · Molecular Therapy · 2007 · 214 citations · Full text

, , +13

Linear DNAs Concatemerize in Vivo and Result in Sustained Transgene Expression in Mouse Liver

Zhiying Chen, Stephen R. Yant, Cheng-Yi He et al. · Molecular Therapy · 2001 · 191 citations · Full text

, , +15

Effect of the E4 region on the persistence of transgene expression from adenovirus vectors

Donna Armentano, Joseph Zabner, Carol R. Sacks et al. · Journal of Virology · 1997 · 189 citations · Full text

, , +13

1–5 of 50

Authors

369

  1. RO
    Richard O. Snyder

    University of Florida, United States

    4 publications · 758 citations

    4

    h-index

  2. MA
    Mark A. Kay

    Stanford University, United States

    4 publications · 1K citations

    4

    h-index

  3. CL
    Caroline Le Guiner

    Inserm, France

    3 publications · 173 citations

    3

    h-index

  4. MP
    Magalie Penaud‐Budloo

    Inserm, France

    3 publications · 173 citations

    3

    h-index

  5. PM
    Philippe Moullier

    Inserm, France

    3 publications · 173 citations

    3

    h-index

1–5 of 369

Institutions

130

  1. University of Florida

    Gainesville, United States

    5 h-index

    13 publications

    530 citations

  2. Inserm

    Paris, France

    4 h-index

    28 publications

    1.8K citations

  3. Stanford University

    Stanford, United States

    4 h-index

    16 publications

    2.4K citations

  4. University of Washington

    Seattle, United States

    3 h-index

    11 publications

    3.1K citations

  5. Genethon (France)

    Évry-Courcouronnes, France

    3 h-index

    6 publications

    346 citations

  6. Centre de Coopération Internationale en Recherche Agronomique pour le Développement

    Paris, France

    3 h-index

    6 publications

    118 citations

  7. Genesys (United States)

    Daly City, United States

    2 h-index

    8 publications

    2.4K citations

  8. Institut Pasteur

    Paris, France

    2 h-index

    7 publications

    1.8K citations

1–8 of 130

Venues

  1. Molecular Therapy

    8 publications · 906 citations

    8

    h-index

  2. Human Gene Therapy

    6 publications · 504 citations

    6

    h-index

  3. Journal of Virology

    JVI · 6 publications · 516 citations

    6

    h-index

  4. PLoS ONE

    3 publications · 54 citations

    3

    h-index

  5. Gene Therapy

    3 publications · 252 citations

    3

    h-index

1–5