Concepedia

Vector Genome Engineering

Vector Genome Engineering is a methodological framework within molecular biotechnology that involves the precise modification of genetic sequences in viral or non-viral vectors to optimize their functionality, specificity, and safety for targeted gene delivery in therapeutic and research applications.

36

Publications

2.4K

Citations

254

Authors

96

Institutions

Publications per year

2017–2026

12

Parents

Publications

36

Cross-Packaging of a Single Adeno-Associated Virus (AAV) Type 2 Vector Genome into Multiple AAV Serotypes Enables Transduction with Broad Specificity

Joseph E. Rabinowitz, Fabienne Rolling, Chengwen Li et al. · Journal of Virology · 2002 · 750 citations · Full text

, , +14

Recombinant Adenovirus Deleted of All Viral Genes for Gene Therapy of Cystic Fibrosis

Krishna J. Fisher, HESTER CHOI, John F. Burda et al. · Virology · 1996 · 292 citations · Full text

, , +13

Comprehensive genomic access to vector integration in clinical gene therapy

Richard Gabriel, Ralph Eckenberg, Anna Paruzynski et al. · Nature Medicine · 2009 · 186 citations

, , +14

Development of virus vectors for gene therapy of β chain hemoglobinopathies: flanking with a chromatin insulator reduces γ-globin gene silencing in vivo

David W. Emery, Evangelia Yannaki, Julie Tubb et al. · Blood · 2002 · 116 citations · Full text

, , +17

Inverted Terminal Repeat Sequences Are Important for Intermolecular Recombination and Circularization of Adeno-Associated Virus Genomes

Ziying Yan, Roman Žák, Yulong Zhang et al. · Journal of Virology · 2004 · 104 citations

, , +14

1–5 of 36

Authors

254

  1. YY
    Yongping Yue

    University of Missouri, United States

    3 publications · 97 citations

    3

    h-index

  2. DD
    Dongsheng Duan

    University of Missouri, United States

    3 publications · 97 citations

    3

    h-index

  3. CL
    Chengwen Li

    University of North Carolina at Chapel Hill, United States

    2 publications · 789 citations

    2

    h-index

  4. GY
    Gang Yao

    University of Missouri, United States

    2 publications · 47 citations

    2

    h-index

  5. TB
    Thais B. Watkins

    Missouri College, United States

    2 publications · 47 citations

    2

    h-index

1–5 of 254

Institutions

96

  1. Missouri College

    Brentwood, United States

    3 h-index

    4 publications

    116 citations

  2. University of Pennsylvania

    Philadelphia, United States

    3 h-index

    12 publications

    2.5K citations

  3. University of Missouri

    Columbia, United States

    3 h-index

    22 publications

    707 citations

  4. Vector (United States)

    Tucson, United States

    2 h-index

    5 publications

    234 citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    7 publications

    79 citations

  6. University of Florida

    Gainesville, United States

    2 h-index

    5 publications

    66 citations

  7. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    2 h-index

    8 publications

    1K citations

  8. The San Raffaele Telethon Institute for Gene Therapy

    Milan, Italy

    2 h-index

    8 publications

    1.3K citations

1–8 of 96

Venues

  1. Gene Therapy

    6 publications · 193 citations

    6

    h-index

  2. Journal of Virology

    JVI · 3 publications · 927 citations

    3

    h-index

  3. Virology

    3 publications · 323 citations

    3

    h-index

  4. Viruses

    2 publications · 111 citations

    2

    h-index

  5. Molecular Therapy

    2 publications · 81 citations

    2

    h-index

1–5