Vasculogenic Differentiation is a mesodermal differentiation process in which pluripotent stem cells commit to an endothelial lineage, forming de novo blood vessels through the assembly of vascular endothelial cells from angioblast precursors during embryonic development.
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Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors
Jun K. Yamashita, Hiroshi Itoh, Masanori Hirashima et al. · Nature · 2000 · 1.4K citations
In vitro differentiation of endothelial cells from AC133-positive progenitor cells
Ursula M. Gehling, Süleyman Ergün, Udo Schumacher et al. · Blood · 2000 · 999 citations
Conversion of vascular endothelial cells into multipotent stem-like cells
Damian Medici, Eileen M. Shore, Vitali Lounev et al. · Nature Medicine · 2010 · 665 citations
Vasculogenesis and angiogenesis in embryonic-stem-cell-derived embryoid bodies
Werner Risau, Hannu Sariola, Hans‐Günter Zerwes et al. · Development · 1988 · 661 citations
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Max Planck Institute for Heart and Lung Research, Germany
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Indiana University – Purdue University Indianapolis, United States
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Medical University of South Carolina, United States
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- Developmental Dynamics
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