Concepedia

Uremia-associated Binding Changes

Uremia-Associated Binding Changes is a pathophysiological construct that denotes altered protein-ligand interaction dynamics due to uremic toxin accumulation in chronic kidney disease, distinguishing it from other causes of protein binding variability by its specific association with uremia-induced biochemical perturbations.

62

Publications

3K

Citations

204

Authors

64

Institutions

Publications per year

2017–2026

3

Parents

Publications

62

Protein Binding of Diphenylhydantoin and Desmethylimipramine in Plasma from Patients with Poor Renal Function

Marcus M. Reidenberg, Ingegerd Odar‐Cederlöf, Christer von Bahr et al. · New England Journal of Medicine · 1971 · 296 citations

, , +15

Behavior of non-protein-bound and protein-bound uremic solutes during daily hemodialysis

Riccardo Maria Fagugli, Rita De Smet, U. Buoncristianí et al. · American Journal of Kidney Diseases · 2002 · 165 citations

, , +14

Morphine and phenytoin binding to plasma proteins in renal and hepatic failure

George D. Olsen, William M. Bennett, George A. Porter · Clinical Pharmacology & Therapeutics · 1975 · 161 citations

, , +17

Protein binding of drugs in uremic and normal serum: The role of endogenous binding inhibitors

Ingvar Sjöholm, Anita Kober, Ingegerd Odar‐Cederlöf · Biochemical Pharmacology · 1976 · 161 citations

, , +16

Kinetics of diphenylhydantoin in uraemic patients: Consequences of decreased plasma protein binding

I. Odar-Cederl�f, O. Borg� · European Journal of Clinical Pharmacology · 1974 · 124 citations

, , +3

1–5 of 62

Authors

204

  1. IO
    Ingegerd Odar‐Cederlöf

    Karolinska University Hospital, Sweden

    5 publications · 630 citations

    5

    h-index

  2. PF
    Paul F. Gulyassy

    University of California, Davis, United States

    4 publications · 131 citations

    4

    h-index

  3. LA
    Linda A. Stanfel

    University of California, Davis, United States

    4 publications · 110 citations

    4

    h-index

  4. EA
    Elizabeth A. Jarrard

    University of California, Davis, United States

    3 publications · 89 citations

    3

    h-index

  5. TA
    Thomas A. Depner

    University of California, Davis, United States

    3 publications · 100 citations

    3

    h-index

1–5 of 204

Institutions

64

  1. Karolinska University Hospital

    Stockholm, Sweden

    6 h-index

    11 publications

    880 citations

  2. Karolinska Institutet

    Stockholm, Sweden

    4 h-index

    9 publications

    685 citations

  3. University of California, Davis

    Davis, United States

    4 h-index

    14 publications

    505 citations

  4. VIB-KU Leuven Center for Microbiology

    Leuven, Belgium

    2 h-index

    5 publications

    504 citations

  5. United States Department of Veterans Affairs

    Washington, United States

    2 h-index

    7 publications

    180 citations

  6. Ghent University Hospital

    Ghent, Belgium

    2 h-index

    10 publications

    955 citations

  7. Stobhill Hospital

    Glasgow, United Kingdom

    2 h-index

    5 publications

    150 citations

  8. KU Leuven

    Leuven, Belgium

    2 h-index

    7 publications

    742 citations

1–8 of 64

Venues

  1. PubMed

    Repository · 8 publications · 283 citations

    8

    h-index

  2. Clinical Pharmacology & Therapeutics

    CPT · 7 publications · 527 citations

    7

    h-index

  3. ˜The œNephron journals/Nephron journals

    6 publications · 130 citations

    6

    h-index

  4. Biochemical Pharmacology

    6 publications · 252 citations

    6

    h-index

  5. Kidney International

    3 publications · 145 citations

    3

    h-index

1–5