Concepedia

Upstream Regulatory Elements

Upstream Regulatory Elements is a cis-acting genomic region located upstream of a transcription start site that modulates gene expression by serving as a binding platform for transcription factors and regulatory proteins, thereby distinguishing it from other regulatory elements through its positional and functional specificity in promoter architecture and viral gene regulation.

1.3K

Publications

98.1K

Citations

5.8K

Authors

1.3K

Institutions

Publications per year

2017–2026

98

Variants

Ures

Parents

Publications

1.3K

Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region

Klaus‐Peter Lesch, Dietmar Bengel, Armin Heils et al. · Science · 1996 · 5.2K citations

, , +17

GREAT improves functional interpretation of cis-regulatory regions

Cory Y. McLean, Dave Bristor, Michael Hiller et al. · Nature Biotechnology · 2010 · 5K citations

, , +12

Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide.

Charles J. Lowenstein, Evan Alley, Pravin Raval et al. · Proceedings of the National Academy of Sciences · 1993 · 1.1K citations

, , +17

Adaptive Evolution of Pelvic Reduction in Sticklebacks by Recurrent Deletion of a <i>Pitx1</i> Enhancer

Yingguang Frank Chan, Melissa E. Marks, Felicity C. Jones et al. · Science · 2009 · 1.1K citations · Full text

, , +14

A regulatory upstream promoter element in the Drosophila Hsp 70 heat-shock gene

Hugh R.B. Pelham · Cell · 1982 · 1K citations

, , +16

1–5 of 1.3K

Authors

5.8K

  1. LK
    Larry Kedes

    University of Southern California, United States

    7 publications · 975 citations

    7

    h-index

  2. DR
    Douglas R. Higgs

    John Radcliffe Hospital, United Kingdom

    7 publications · 835 citations

    7

    h-index

  3. JH
    John H. Nilson

    Case Western Reserve University, United States

    7 publications · 384 citations

    7

    h-index

  4. LT
    Louise T. Chow

    University of Alabama at Birmingham, United States

    6 publications · 328 citations

    6

    h-index

  5. JD
    James Darnell

    Rockefeller University, United States

    6 publications · 616 citations

    6

    h-index

1–5 of 5.8K

Institutions

1.3K

  1. Harvard University

    Cambridge, United States

    29 h-index

    125 publications

    10.1K citations

  2. National Institutes of Health

    Bethesda, United States

    28 h-index

    139 publications

    18.6K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    26 h-index

    88 publications

    13.2K citations

  4. National Cancer Institute

    Bethesda, United States

    20 h-index

    87 publications

    6.5K citations

  5. Inserm

    Paris, France

    19 h-index

    76 publications

    4.2K citations

  6. University of Washington

    Seattle, United States

    18 h-index

    60 publications

    5.1K citations

  7. Yale University

    New Haven, United States

    16 h-index

    49 publications

    3.4K citations

  8. Stanford University

    Stanford, United States

    16 h-index

    51 publications

    49.4K citations

1–8 of 1.3K

Venues

  1. Molecular and Cellular Biology

    MCB · 149 publications · 12.2K citations

    64

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  2. Journal of Biological Chemistry

    JBC · 133 publications · 9.5K citations

    59

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 68 publications · 7.9K citations

    48

    h-index

  4. Nucleic Acids Research

    59 publications · 4K citations

    35

    h-index

  5. Journal of Virology

    JVI · 48 publications · 2.8K citations

    33

    h-index

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