Concepedia

Upstream Bioprocess Optimization

Upstream Bioprocess Optimization is a systematic approach within biopharmaceutical development that enhances the efficiency, yield, and scalability of vaccine production by refining cell culture conditions, bioreactor parameters, and process control strategies prior to product harvest.

5

Publications

177

Citations

18

Authors

9

Institutions

Publications per year

2017–2026

2

Parents

Publications

5

Moving towards an era of hybrid modelling: advantages and challenges of coupling mechanistic and data-driven models for upstream pharmaceutical bioprocesses

Apostolos Tsopanoglou, Ioscani Jiménez del Val · Current Opinion in Chemical Engineering · 2021 · 99 citations · Full text

, , +17

Optimal design of upstream processes in biotransformation technologies

Endrit Dheskali, Katerina Michailidi, Aline Machado de Castro et al. · Bioresource Technology · 2016 · 29 citations

, , +16

Upstream process optimization of polyhydroxybutyrate (PHB) by Alcaligenes latus using two-stage batch and fed-batch fermentation strategies

Bingqing Wang, Ratna R. Sharma-Shivappa, Jonathan W. Olson et al. · Bioprocess and Biosystems Engineering · 2012 · 27 citations

, , +17

Analysis of Transformed Upstream Bioprocess Data Provides Insights into Biological System Variation

Anne Richelle, Boung Wook Lee, Rui M. C. Portela et al. · Biotechnology Journal · 2020 · 12 citations

, , +17

Designing Robust Biotechnological Processes Regarding Variabilities Using Multi-Objective Optimization Applied to a Biopharmaceutical Seed Train Design

Tanja Hernández Rodríguez, Anton Sekulic, Markus Lange‐Hegermann et al. · Processes · 2022 · 11 citations · Full text

, , +17

1–5 of 5

Authors

18

  1. MV
    Moritz von Stosch

    Newcastle University, United Kingdom

    1 publications · 12 citations

    1

    h-index

  2. AT
    Apostolos Tsopanoglou

    University College Dublin, Ireland

    1 publications · 99 citations

    1

    h-index

  3. MA
    Meerza Abdul Razak

    Sri Venkateswara University, India

    1 publications · 10 citations

    1

    h-index

  4. IK
    Ioannis K. Kookos

    University of Patras, Greece

    1 publications · 29 citations

    1

    h-index

  5. RM
    Rui M. C. Portela

    Universidade Nova de Lisboa, Portugal

    1 publications · 12 citations

    1

    h-index

1–5 of 18

Institutions

9

  1. Cell Culture Company (United States)

    Minneapolis, United States

    1 h-index

    2 publications

    24 citations

  2. Sri Venkateswara University

    Tirumala - Tirupati, India

    1 h-index

    1 publications

    10 citations

  3. Petrobras (Brazil)

    Rio de Janeiro, Brazil

    1 h-index

    1 publications

    29 citations

  4. GlaxoSmithKline (Switzerland)

    Bern, Switzerland

    1 h-index

    3 publications

    36 citations

  5. Agricultural University of Athens

    Athens, Greece

    1 h-index

    1 publications

    29 citations

  6. University of Patras

    Pátrai, Greece

    1 h-index

    3 publications

    87 citations

  7. Natco Pharma (India)

    Hyderabad, India

    1 h-index

    1 publications

    10 citations

  8. University College Dublin

    Dublin, Ireland

    1 h-index

    2 publications

    198 citations

1–8 of 9

Venues

  1. Current Opinion in Chemical Engineering

    1 publications · 99 citations

    1

    h-index

  2. Bioresource Technology

    1 publications · 29 citations

    1

    h-index

  3. Biotechnology Journal

    1 publications · 12 citations

    1

    h-index

  4. Bioprocess and Biosystems Engineering

    1 publications · 27 citations

    1

    h-index

  5. 3 Biotech

    1 publications · 10 citations

    1

    h-index

1–5