Concepedia

Tumor Vascular Normalization

Tumor Vascular Normalization is a therapeutic strategy in cancer biology that selectively remodels the abnormal tumor vasculature to restore structural and functional integrity, thereby improving perfusion and reducing hypoxia without inducing widespread vessel pruning.

446

Publications

37.7K

Citations

3.5K

Authors

957

Institutions

Publications per year

2017–2026

180

Parents

Publications

446

Vascular Normalization by Vascular Endothelial Growth Factor Receptor 2 Blockade Induces a Pressure Gradient Across the Vasculature and Improves Drug Penetration in Tumors

Ricky T. Tong, Yves Boucher, Sergey V. Kozin et al. · Cancer Research · 2004 · 1.2K citations · Full text

, , +17

Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation

Frank Winkler, Sergey V. Kozin, Ricky T. Tong et al. · Cancer Cell · 2004 · 1.2K citations · Full text

, , +12

Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner

Vikash P. Chauhan, Triantafyllos Stylianopoulos, John D. Martin et al. · Nature Nanotechnology · 2012 · 1.1K citations · Full text

, , +14

Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming

Lin Tian, Amit Goldstein, Hai Wang et al. · Nature · 2017 · 852 citations

, , +16

Heterozygous Deficiency of PHD2 Restores Tumor Oxygenation and Inhibits Metastasis via Endothelial Normalization

Massimiliano Mazzone, Daniela Dettori, Rodrigo Leite de Oliveira et al. · Cell · 2009 · 812 citations · Full text

, , +17

1–5 of 446

Authors

3.5K

  1. DG
    Dan G. Duda

    Massachusetts General Hospital, United States

    10 publications · 2.1K citations

    10

    h-index

  2. TS
    Triantafyllos Stylianopoulos

    University of Cyprus, Cyprus

    9 publications · 2.6K citations

    9

    h-index

  3. DF
    Dai Fukumura

    Massachusetts General Hospital, United States

    8 publications · 3.9K citations

    8

    h-index

  4. YH
    Yuhui Huang

    Massachusetts General Hospital, United States

    7 publications · 725 citations

    7

    h-index

  5. TT
    Tracy T. Batchelor

    Massachusetts General Hospital, United States

    7 publications · 1.7K citations

    7

    h-index

1–5 of 3.5K

Institutions

957

  1. Massachusetts General Hospital

    Boston, United States

    22 h-index

    158 publications

    60.8K citations

  2. Harvard University

    Cambridge, United States

    20 h-index

    150 publications

    59.9K citations

  3. Inserm

    Paris, France

    14 h-index

    96 publications

    5.1K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    11 h-index

    61 publications

    4.2K citations

  5. Heidelberg University

    Heidelberg, Germany

    11 h-index

    76 publications

    7.1K citations

  6. Sun Yat-sen University

    Guangzhou, China

    11 h-index

    55 publications

    2K citations

  7. Chinese Academy of Sciences

    Beijing, China

    10 h-index

    46 publications

    2.1K citations

  8. German Cancer Research Center

    Heidelberg, Germany

    10 h-index

    49 publications

    4K citations

1–8 of 957

Venues

  1. Cancer Research

    27 publications · 4.9K citations

    25

    h-index

  2. Clinical Cancer Research

    16 publications · 2.1K citations

    16

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 16 publications · 3.5K citations

    16

    h-index

  4. PubMed

    Repository · 15 publications · 2.2K citations

    14

    h-index

  5. Scientific Reports

    10 publications · 499 citations

    10

    h-index

1–5