Concepedia

Transporter Expression Variability

Transporter Expression Variability is a pharmacokinetic determinant characterized by interindividual differences in the abundance or activity of membrane transport proteins due to genetic, epigenetic, or environmental factors that influence drug disposition and response.

25

Publications

2.4K

Citations

159

Authors

66

Institutions

Publications per year

2017–2026

7

Parents

Publications

25

Interindividual variability of canalicular ATP-binding-cassette (ABC)–transporter expression in human liver

Yvonne Meier, Christiane Pauli‐Magnus, Ulrich M. Zanger et al. · Hepatology · 2006 · 220 citations

, , +17

Interindividual Variability in Hepatic Organic Anion-Transporting Polypeptides and P-Glycoprotein (ABCB1) Protein Expression: Quantification by Liquid Chromatography Tandem Mass Spectroscopy and Influence of Genotype, Age, and Sex

Bhagwat Prasad, Raymond Evers, Anshul Gupta et al. · Drug Metabolism and Disposition · 2013 · 194 citations · Full text

, , +16

Gender-related differences in ion-channel and transporter subunit expression in non-diseased human hearts

Nathalie Gaborit, András Varró, Sabrina Le Bouter et al. · Journal of Molecular and Cellular Cardiology · 2010 · 194 citations

, , +16

Interspecies Variability in Expression of Hepatobiliary Transporters across Human, Dog, Monkey, and Rat as Determined by Quantitative Proteomics

Li Wang, Bhagwat Prasad, Laurent Salphati et al. · Drug Metabolism and Disposition · 2014 · 188 citations

, , +14

Analysis of drug transporter expression in human intestinal Caco‐2 cells by real‐time PCR

Nathalie Maubon, Marc Le Vée, Lina Fossati et al. · Fundamental and Clinical Pharmacology · 2007 · 183 citations

, , +15

1–5 of 25

Authors

159

  1. FZ
    Feng Zhu

    Zhejiang University, China

    2 publications · 163 citations

    2

    h-index

  2. XJ
    Xue Jia

    Cleveland Clinic, United States

    2 publications · 163 citations

    2

    h-index

  3. BP
    Bhagwat Prasad

    University of Washington, United States

    2 publications · 382 citations

    2

    h-index

  4. JY
    Jiayi Yin

    Zhejiang University, China

    2 publications · 163 citations

    2

    h-index

  5. LY
    Lushan Yu

    Zhejiang University, China

    2 publications · 163 citations

    2

    h-index

1–5 of 159

Institutions

66

  1. National Institutes of Health

    Bethesda, United States

    3 h-index

    18 publications

    2.4K citations

  2. National Cancer Institute

    Bethesda, United States

    2 h-index

    13 publications

    1.8K citations

  3. Inserm

    Paris, France

    2 h-index

    7 publications

    1.3K citations

  4. University of Manchester

    Manchester, United Kingdom

    2 h-index

    11 publications

    743 citations

  5. AstraZeneca (United States)

    Wilmington, United States

    2 h-index

    16 publications

    3.1K citations

  6. PharmacoGenetics (China)

    Hong Kong, China

    2 h-index

    16 publications

    3.1K citations

  7. First Affiliated Hospital Zhejiang University

    Hangzhou, China

    2 h-index

    12 publications

    473 citations

  8. Merck & Co., Inc., Rahway, NJ, USA (United States)

    Rahway, United States

    2 h-index

    16 publications

    3.1K citations

1–8 of 66

Venues

  1. Drug Metabolism and Disposition

    6 publications · 710 citations

    6

    h-index

  2. Nucleic Acids Research

    2 publications · 163 citations

    2

    h-index

  3. Biomedicine & Pharmacotherapy

    1 publications · 74 citations

    1

    h-index

  4. Molecular Pharmaceutics

    1 publications · 56 citations

    1

    h-index

  5. Hepatology Communications

    1 publications · 28 citations

    1

    h-index

1–5