Concepedia

Transform-based Retrosynthesis

Transform-Based Retrosynthesis is a retrosynthetic approach that systematically deconstructs target molecules by applying known reaction transforms in reverse, distinguished by its reliance on predefined, generalized operations derived from empirical reaction knowledge to identify feasible synthetic pathways.

7

Publications

611

Citations

21

Authors

7

Institutions

Publications per year

2017–2026

4

Parents

Publications

7

Radical Retrosynthesis

Joel M. Smith, Stephen J. Harwood, Phil S. Baran · Accounts of Chemical Research · 2018 · 297 citations

, , +9

Computer‐aided synthesis design: 40 years on

Anthony Cook, A. Peter Johnson, James Law et al. · Wiley Interdisciplinary Reviews Computational Molecular Science · 2011 · 135 citations

, , +8

Total Synthesis of Paspaline A and Emindole PB Enabled by Computational Augmentation of a Transform-Guided Retrosynthetic Strategy

Daria E. Kim, Joshua E. Zweig, Timothy R. Newhouse · Journal of the American Chemical Society · 2019 · 66 citations

, , +14

PaRoutes: towards a framework for benchmarking retrosynthesis route predictions

Samuel Genheden, Esben Jannik Bjerrum · Digital Discovery · 2022 · 53 citations · Full text

, , +10

Application of chemical transforms in synchem2, a computer program for organic synthesis route discovery

T.D.L. Larsen, H. Gelernter · Computers & Chemistry · 1978 · 35 citations

, , +8

1–5 of 7

Authors

21

  1. DE
    Daria E. Kim

    Massachusetts Institute of Technology, United States

    1 publications · 66 citations

    1

    h-index

  2. SG
    Samuel Genheden

    Lund University, Sweden

    1 publications · 53 citations

    1

    h-index

  3. PS
    Phil S. Baran

    Scripps Research Institute, United States

    1 publications · 297 citations

    1

    h-index

  4. EJ
    Esben Jannik Bjerrum

    AstraZeneca (Sweden), Sweden

    1 publications · 53 citations

    1

    h-index

  5. NK
    Nikolay Kochev

    IDEAconsult, Bulgaria

    1 publications · 13 citations

    1

    h-index

1–5 of 21

Institutions

7

  1. AstraZeneca (Sweden)

    Södertälje, Sweden

    1 h-index

    2 publications

    106 citations

  2. Radboud University Nijmegen

    Nijmegen, The Netherlands

    1 h-index

    2 publications

    24 citations

  3. University of Leeds

    Leeds, United Kingdom

    1 h-index

    2 publications

    270 citations

  4. Yale University

    New Haven, United States

    1 h-index

    3 publications

    198 citations

  5. Stony Brook University

    Stony Brook, United States

    1 h-index

    3 publications

    105 citations

  6. Plovdiv University

    Plovdiv, Bulgaria

    1 h-index

    3 publications

    39 citations

  7. Scripps Research Institute

    San Diego, United States

    1 h-index

    3 publications

    891 citations

  8. University of Silesia in Katowice

    Katowice, Poland

    1 publications

    19 citations

1–8 of 7

Venues

  1. Computers & Chemistry

    1 publications · 35 citations

    1

    h-index

  2. Data

    1 publications · 13 citations

    1

    h-index

  3. Digital Discovery

    1 publications · 53 citations

    1

    h-index

  4. 1

    h-index

  5. 1

    h-index

1–5