Concepedia

Transcription Initiation Complex

The Transcription Initiation Complex is a macromolecular assembly that forms at gene promoters and serves as the functional unit for initiating transcription by positioning RNA polymerase and associated general transcription factors to enable accurate promoter recognition and DNA unwinding.

1.2K

Publications

95.4K

Citations

4.1K

Authors

926

Institutions

Publications per year

2017–2026

155

Variants

PicTranscription Pre-initiation Complex

Parents

Publications

1.2K

A Chromatin Landmark and Transcription Initiation at Most Promoters in Human Cells

Matthew G. Guenther, Stuart S. Levine, Laurie A. Boyer et al. · Cell · 2007 · 2K citations · Full text

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Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription

Philip Komarnitsky, Eun‐Jung Cho, Stephen Buratowski · Genes & Development · 2000 · 1.1K citations · Full text

, , +17

Five intermediate complexes in transcription initiation by RNA polymerase II

Stephen Buratowski, Steven Hahn, Leonard Guarente et al. · Cell · 1989 · 1K citations

, , +16

The role of general initiation factors in transcription by RNA polymerase II

Ryan K. Roeder · Trends in Biochemical Sciences · 1996 · 998 citations

, , +14

Structural Basis of Transcription: An RNA Polymerase II Elongation Complex at 3.3 Å Resolution

Averell Gnatt, Patrick Cramer, Jianhua Fu et al. · Science · 2001 · 903 citations · Full text

, , +17

1–5 of 1.2K

Authors

4.1K

  1. RG
    Robert G. Roeder

    Rockefeller University, United States

    34 publications · 5.4K citations

    29

    h-index

  2. RH
    Richard H. Ebright

    Rutgers, The State University of New Jersey, United States

    17 publications · 2.7K citations

    17

    h-index

  3. PC
    Patrick Cramer

    Max Planck Institute for Biophysical Chemistry, Germany

    18 publications · 2.8K citations

    17

    h-index

  4. DR
    Danny Reinberg

    Howard Hughes Medical Institute, United States

    15 publications · 2.5K citations

    15

    h-index

  5. AS
    André Sentenac

    Centre de Génétique Moléculaire, France

    13 publications · 789 citations

    13

    h-index

1–5 of 4.1K

Institutions

926

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    50 h-index

    172 publications

    24.6K citations

  2. Rockefeller University

    New York, United States

    47 h-index

    212 publications

    27.8K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    32 h-index

    189 publications

    12.7K citations

  4. Harvard University

    Cambridge, United States

    31 h-index

    95 publications

    14.6K citations

  5. University of Wisconsin–Madison

    Madison, United States

    31 h-index

    141 publications

    13.2K citations

  6. Rutgers, The State University of New Jersey

    New Brunswick, United States

    30 h-index

    115 publications

    11.6K citations

  7. National Institutes of Health

    Bethesda, United States

    27 h-index

    131 publications

    8K citations

  8. Inserm

    Paris, France

    26 h-index

    127 publications

    10.3K citations

1–8 of 926

Venues

  1. Journal of Biological Chemistry

    JBC · 205 publications · 12.9K citations

    64

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 114 publications · 8.2K citations

    56

    h-index

  3. Molecular and Cellular Biology

    MCB · 98 publications · 5.9K citations

    45

    h-index

  4. Nucleic Acids Research

    97 publications · 4.1K citations

    36

    h-index

  5. Genes & Development

    35 publications · 7K citations

    35

    h-index

1–5