Transcription Conflicts is a molecular-genetic phenomenon in which the machineries of transcription and DNA replication collide on the same DNA template, leading to replication stress and potential genomic instability due to opposing directional movement or spatial overlap of the two processes.
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Co-directional replication–transcription conflicts lead to replication restart
Houra Merrikh, Cristina Machón, William H. Grainger et al. · Nature · 2011 · 188 citations · Full text
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Centre National de la Recherche Scientifique
Paris, France
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Centro Andaluz de Biología Molecular y Medicina Regenerativa
Seville, Spain
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21 publications
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University of Washington
Seattle, United States
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Universidad de Sevilla
Seville, Spain
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Birmingham, United Kingdom
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University of Nottingham
Nottingham, United Kingdom
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University of British Columbia
Vancouver, Canada
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Terry Fox Research Institute
Vancouver, Canada
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