Concepedia

Toxicant Detoxification

Toxicant Detoxification is a biochemical process within the category of detoxification mechanisms that specifically involves the enzymatic conjugation of toxicants with glutathione to enhance their water solubility and facilitate excretion, thereby reducing their biological reactivity and potential for cellular damage.

342

Publications

16.2K

Citations

1.5K

Authors

546

Institutions

Publications per year

2017–2026

85

Parents

Publications

342

Identification of an enzymatically formed glutathione conjugate of the cyanobacterial hepatotoxin microcystin-LR: the first step of detoxication

Stephan Pflugmacher, Claudia Wiegand, Axel Oberemm et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 1998 · 552 citations

, , +16

Development of isothiocyanate-enriched broccoli, and its enhanced ability to induce phase 2 detoxification enzymes in mammalian cells

Richard Mithen, Kathy Faulkner, R. Magrath et al. · Theoretical and Applied Genetics · 2003 · 271 citations

, , +16

ROLE OF ENZYMES IN THE REMEDIATION OF POLLUTED ENVIRONMENTS

M.A. Rao, Rosalia Scelza, Riccardo Scotti et al. · Journal of soil science and plant nutrition · 2010 · 252 citations · Full text

, , +17

The detoxification of lead in Sedum alfredii H. is not related to phytochelatins but the glutathione

Dharmendra K. Gupta, Huagang Huang, Xiaoe Yang et al. · Journal of Hazardous Materials · 2009 · 235 citations

, , +12

Detoxication Mechanisms: The Metabolism and Detoxication of Drugs, Toxic Substances and Other Organic Compounds

Bernard E. Conley · JAMA · 1960 · 217 citations

, , +11

1–5 of 342

Authors

1.5K

  1. RT
    R. T. Williams

    St Mary's Hospital, United Kingdom

    7 publications · 401 citations

    7

    h-index

  2. JN
    J. N. Smith

    Bedford Institute of Oceanography, Canada

    6 publications · 162 citations

    6

    h-index

  3. DV
    D. V. Parke

    St Mary's Hospital, United Kingdom

    5 publications · 349 citations

    5

    h-index

  4. PX
    Ping Xie

    Institute of Hydrobiology, China

    4 publications · 104 citations

    4

    h-index

  5. JP
    James P. Kutney

    University of British Columbia, Canada

    4 publications · 94 citations

    4

    h-index

1–5 of 1.5K

Institutions

546

  1. St Mary's Hospital

    Kettering, United Kingdom

    13 h-index

    33 publications

    1.6K citations

  2. Chinese Academy of Sciences

    Beijing, China

    9 h-index

    38 publications

    1.4K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    20 publications

    811 citations

  4. Institute of Hydrobiology

    Wuhan, China

    5 h-index

    33 publications

    1.3K citations

  5. University of York

    York, United Kingdom

    5 h-index

    28 publications

    2K citations

  6. University of Florida

    Gainesville, United States

    4 h-index

    11 publications

    382 citations

  7. University of Liverpool

    Liverpool, United Kingdom

    4 h-index

    13 publications

    455 citations

  8. Huazhong Agricultural University

    Wuhan, China

    4 h-index

    15 publications

    414 citations

1–8 of 546

Venues

  1. Biochemical Journal

    16 publications · 684 citations

    14

    h-index

  2. Chemosphere

    12 publications · 516 citations

    11

    h-index

  3. PubMed

    Repository · 11 publications · 262 citations

    10

    h-index

  4. Toxicology and Applied Pharmacology

    TAAP · 7 publications · 342 citations

    7

    h-index

  5. Pesticide Biochemistry and Physiology

    PBP · 7 publications · 366 citations

    7

    h-index

1–5