Concepedia

Top-down Proteomics Quantification

Top-Down Proteomics Quantification is a protein quantification method that directly measures intact proteins by mass spectrometry, distinguishing itself from bottom-up approaches through the preservation and analysis of whole proteins to enable precise characterization of proteoforms and their stoichiometric abundances.

62

Publications

3.6K

Citations

313

Authors

98

Institutions

Publications per year

2017–2026

38

Parents

Publications

62

Peer Reviewed: Top-Down Proteomics

Neil L. Kelleher · Analytical Chemistry · 2004 · 496 citations

, , +16

On the Scalability and Requirements of Whole Protein Mass Spectrometry

Philip D. Compton, Leonid Zamdborg, Paul M. Thomas et al. · Analytical Chemistry · 2011 · 242 citations

, , +17

Top-Down Quantitative Proteomics Identified Phosphorylation of Cardiac Troponin I as a Candidate Biomarker for Chronic Heart Failure

Jiang Zhang, Moltu J. Guy, Holly S. Norman et al. · Journal of Proteome Research · 2011 · 192 citations · Full text

, , +17

Informed-Proteomics: open-source software package for top-down proteomics

Jungkap Park, Paul Piehowski, Christopher Wilkins et al. · Nature Methods · 2017 · 172 citations

, , +12

Top-down characterization of endogenous protein complexes with native proteomics

Owen S. Skinner, Nicole A. Haverland, Luca Fornelli et al. · Nature Chemical Biology · 2017 · 169 citations

, , +16

1–5 of 62

Authors

313

  1. NL
    Neil L. Kelleher

    Northwestern University, United States

    16 publications · 1.5K citations

    16

    h-index

  2. YG
    Ying Ge

    University of Wisconsin–Madison, United States

    9 publications · 640 citations

    9

    h-index

  3. RT
    Ryan T. Fellers

    Northwestern University, United States

    6 publications · 254 citations

    6

    h-index

  4. PM
    Paul M. Thomas

    Northwestern University, United States

    6 publications · 465 citations

    6

    h-index

  5. RD
    Richard D. LeDuc

    Northwestern University, United States

    4 publications · 124 citations

    4

    h-index

1–5 of 313

Institutions

98

  1. University of Wisconsin–Madison

    Madison, United States

    13 h-index

    103 publications

    6.3K citations

  2. Northwestern University

    Evanston, United States

    12 h-index

    92 publications

    6K citations

  3. University of Illinois Urbana-Champaign

    Urbana, United States

    5 h-index

    24 publications

    1.7K citations

  4. University of Oklahoma

    Norman, United States

    4 h-index

    18 publications

    569 citations

  5. Energy Center of Wisconsin

    Madison, United States

    4 h-index

    17 publications

    749 citations

  6. Environmental Molecular Sciences Laboratory

    Richland, United States

    3 h-index

    15 publications

    937 citations

  7. Pacific Northwest National Laboratory

    Richland, United States

    3 h-index

    36 publications

    3.5K citations

  8. Baylor College of Medicine

    Houston, United States

    3 h-index

    9 publications

    270 citations

1–8 of 98

Venues

  1. Journal of Proteome Research

    JPR · 17 publications · 709 citations

    16

    h-index

  2. Analytical Chemistry

    12 publications · 1.1K citations

    12

    h-index

  3. Journal of the American Society for Mass Spectrometry

    JASMS · 5 publications · 211 citations

    5

    h-index

  4. Nature Methods

    3 publications · 372 citations

    3

    h-index

  5. Molecular & Cellular Proteomics

    MCP · 3 publications · 105 citations

    3

    h-index

1–5