Concepedia

Thymine Glycol Bypass

Thymine Glycol Bypass is a DNA damage tolerance mechanism belonging to the class of translesion DNA synthesis processes, distinguished by its specific ability to replicate past thymine glycol lesions through the action of specialized DNA polymerases that accommodate the modified base in their active sites.

18

Publications

1K

Citations

82

Authors

35

Institutions

Publications per year

2017–2026

2

Parents

Publications

18

Human DNA Polymerase N (POLN) Is a Low Fidelity Enzyme Capable of Error-free Bypass of 5S-Thymine Glycol

Kei‐ichi Takata, Tatsuhiko Shimizu, Shigenori Iwai et al. · Journal of Biological Chemistry · 2006 · 146 citations · Full text

, , +9

Human DNA Polymerase κ Bypasses and Extends beyond Thymine Glycols during Translesion Synthesis in Vitro, Preferentially Incorporating Correct Nucleotides

Paula L. Fischhaber, Valerie L. Gerlach, William J. Feaver et al. · Journal of Biological Chemistry · 2002 · 107 citations · Full text

, , +15

Sequence dependence for bypass of thymine glycols in DNA by DNA polymerase I

Robert C. Hayes, Jean-Marie Leclerc · Nucleic Acids Research · 1986 · 102 citations · Full text

, , +8

Enzymatic Processing of Uracil Glycol, a Major Oxidative Product of DNA Cytosine

Andrei A. Purmal, Gary W. Lampman, Jeffrey P. Bond et al. · Journal of Biological Chemistry · 1998 · 96 citations · Full text

, , +17

Yeast DNA polymerase zeta (ζ) is essential for error-free replication past thymine glycol

Robert E. Johnson, Sung‐Lim Yu, Satya Prakash et al. · Genes & Development · 2003 · 94 citations · Full text

, , +15

1–5 of 18

Authors

82

  1. RD
    Richard D. Wood

    Genesis Foundation, United States

    4 publications · 317 citations

    4

    h-index

  2. SS
    Susan S. Wallace

    University of Vermont, United States

    4 publications · 248 citations

    4

    h-index

  3. KT
    Kei‐ichi Takata

    Tokyo University of Science, Japan

    3 publications · 238 citations

    3

    h-index

  4. ZH
    Zafer Hatahet

    University of Vermont, United States

    2 publications · 203 citations

    2

    h-index

  5. MS
    Mineaki Seki

    The University of Osaka, Japan

    2 publications · 108 citations

    2

    h-index

1–5 of 82

Institutions

35

  1. University of Vermont

    Burlington, United States

    4 h-index

    17 publications

    908 citations

  2. The University of Texas Medical Branch at Galveston

    Galveston, United States

    2 h-index

    8 publications

    688 citations

  3. The University of Osaka

    Osaka, Japan

    2 h-index

    3 publications

    321 citations

  4. Genesis Foundation

    New York, United States

    2 h-index

    3 publications

    204 citations

  5. Friedrich Schiller University Jena

    Jena, Germany

    1 h-index

    3 publications

    51 citations

  6. National Institute of Infectious Diseases

    Tokyo, Japan

    1 h-index

    1 publications

    39 citations

  7. Litron Laboratories (United States)

    Rochester, United States

    1 h-index

    2 publications

    158 citations

  8. Lomonosov Moscow State University

    Moscow, Russia

    1 h-index

    3 publications

    108 citations

1–8 of 35

Venues

  1. Nucleic Acids Research

    3 publications · 148 citations

    3

    h-index

  2. Journal of Biological Chemistry

    JBC · 3 publications · 349 citations

    3

    h-index

  3. Biochemistry

    3 publications · 117 citations

    3

    h-index

  4. Journal of Bacteriology

    JB · 1 publications · 17 citations

    1

    h-index

  5. The EMBO Journal

    1 publications · 30 citations

    1

    h-index

1–5