Concepedia

Thymic Selection Thresholds

Thymic Selection Thresholds is a theoretical construct in immunology that specifies the quantitative signaling criteria determining the positive and negative selection of immature T cells in the thymus, thereby defining the avidity window that distinguishes self-tolerant T cell survival from clonal deletion.

44

Publications

4.5K

Citations

220

Authors

96

Institutions

Publications per year

2017–2026

6

Parents

Publications

44

Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling

Mark A. Daniëls, Emma Teixeiro, Jason Gill et al. · Nature · 2006 · 580 citations

, , +12

Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice

Michael Huesmann, Bernadette Scott, Paweł Kisielow et al. · Cell · 1991 · 365 citations

, , +12

Altered thymic positive selection and intracellular signals in Cbl-deficient mice

Mayumi Naramura, Hemanta K. Kole, Ren-Ju Hu et al. · Proceedings of the National Academy of Sciences · 1998 · 333 citations

, , +17

Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection

Andrej Košmrlj, Elizabeth L. Read, Qi Ying et al. · Nature · 2010 · 306 citations · Full text

, , +17

Another view of the selective model of thymocyte selection

Susan Chan, Dominic Cosgrove, Caroline Waltzinger et al. · Cell · 1993 · 276 citations

, , +10

1–5 of 44

Authors

220

  1. AK
    Arup K. Chakraborty

    Massachusetts Institute of Technology, United States

    3 publications · 461 citations

    3

    h-index

  2. CM
    Craig M. Walsh

    University of California, Irvine, United States

    2 publications · 51 citations

    2

    h-index

  3. IP
    Immo Prinz

    Medizinische Hochschule Hannover, Germany

    2 publications · 133 citations

    2

    h-index

  4. JJ
    Jörg J. Goronzy

    Mayo Clinic, United States

    2 publications · 95 citations

    2

    h-index

  5. NZ
    Natalia Ziętara

    Medizinische Hochschule Hannover, Germany

    2 publications · 133 citations

    2

    h-index

1–5 of 220

Institutions

96

  1. National Cancer Institute

    Bethesda, United States

    5 h-index

    10 publications

    908 citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    5 h-index

    11 publications

    1.5K citations

  3. National Institutes of Health

    Bethesda, United States

    5 h-index

    17 publications

    2.6K citations

  4. University of California, San Francisco

    San Francisco, United States

    4 h-index

    9 publications

    962 citations

  5. Stanford University

    Stanford, United States

    3 h-index

    14 publications

    719 citations

  6. Massachusetts Institute of Technology

    Cambridge, United States

    3 h-index

    6 publications

    1.2K citations

  7. The Francis Crick Institute

    London, United Kingdom

    2 h-index

    2 publications

    111 citations

  8. Medizinische Hochschule Hannover

    Hanover, Germany

    2 h-index

    9 publications

    399 citations

1–8 of 96

Venues

  1. The Journal of Immunology

    JI · 8 publications · 313 citations

    8

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 7 publications · 786 citations

    7

    h-index

  3. International Immunology

    4 publications · 147 citations

    4

    h-index

  4. Nature

    3 publications · 1.1K citations

    3

    h-index

  5. Immunity

    3 publications · 366 citations

    3

    h-index

1–5