Concepedia

Thioesterase Domain Function

Thioesterase Domain Function is a catalytic domain in nonribosomal peptide synthetase machinery that functions as an enzyme-mediated release mechanism by hydrolyzing or cyclizing the thioester bond between the mature peptide and the carrier protein, thereby facilitating product termination and release.

163

Publications

9.5K

Citations

734

Authors

237

Institutions

Publications per year

2017–2026

30

Parents

Publications

163

Purification and properties of a palmitoyl-protein thioesterase that cleaves palmitate from H-Ras.

Laura A. Camp, Sandra L. Hofmann · Journal of Biological Chemistry · 1993 · 361 citations · Full text

, , +15

Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase

John W. Trauger, Rahul M. Kohli, Henning D. Mootz et al. · Nature · 2000 · 333 citations

, , +12

The tyrocidine biosynthesis operon of Bacillus brevis: complete nucleotide sequence and biochemical characterization of functional internal adenylation domains

Henning D. Mootz, Mohamed A. Marahiel · Journal of Bacteriology · 1997 · 303 citations

, , +14

Identification and Partial Characterization of the Nonribosomal Peptide Synthetase Gene Responsible for Cereulide Production in Emetic <i>Bacillus cereus</i>

Monika Ehling‐Schulz, Nataša Vukov, Anja Schulz et al. · Applied and Environmental Microbiology · 2005 · 286 citations · Full text

, , +13

Genetic Analysis of the Peptide Synthetase Genes for a Cyclic Heptapeptide Microcystin in Microcystis spp.

Tatsuo NISHIZAWA, Munehiko Asayama, Kiyonaga Fujii et al. · The Journal of Biochemistry · 1999 · 261 citations

, , +13

1–5 of 163

Authors

734

  1. CT
    Christopher T. Walsh

    Harvard University, United States

    15 publications · 1.9K citations

    14

    h-index

  2. MA
    Mohamed A. Marahiel

    Philipps University of Marburg, Germany

    11 publications · 1.7K citations

    11

    h-index

  3. CK
    Chaitan Khosla

    Stanford University, United States

    9 publications · 725 citations

    9

    h-index

  4. DE
    David E. Cane

    Brown University, United States

    9 publications · 508 citations

    9

    h-index

  5. DD
    Debra Dunaway‐Mariano

    University of New Mexico, United States

    6 publications · 181 citations

    6

    h-index

1–5 of 734

Institutions

237

  1. Harvard University

    Cambridge, United States

    16 h-index

    61 publications

    8K citations

  2. Philipps University of Marburg

    Marburg, Germany

    11 h-index

    35 publications

    4.7K citations

  3. Brown University

    Providence, United States

    9 h-index

    30 publications

    1.5K citations

  4. Stanford University

    Stanford, United States

    9 h-index

    34 publications

    3K citations

  5. Shanghai Jiao Tong University

    Shanghai, China

    6 h-index

    29 publications

    1.3K citations

  6. University of New Mexico

    Albuquerque, United States

    6 h-index

    23 publications

    707 citations

  7. University of Dundee

    Dundee, United Kingdom

    5 h-index

    32 publications

    973 citations

  8. Chinese Academy of Sciences

    Beijing, China

    5 h-index

    21 publications

    985 citations

1–8 of 237

Venues

  1. Biochemistry

    22 publications · 1.2K citations

    19

    h-index

  2. Journal of Biological Chemistry

    JBC · 17 publications · 1.1K citations

    15

    h-index

  3. Chemistry & Biology

    11 publications · 884 citations

    11

    h-index

  4. Journal of the American Chemical Society

    JACS · 8 publications · 523 citations

    8

    h-index

  5. ChemBioChem

    5 publications · 134 citations

    5

    h-index

1–5