Concepedia

Tfiih Complex Function

TFIIH Complex Function is a molecular mechanism within the nucleotide excision repair pathway that specifically enables the unwinding of DNA around a lesion through the helicase activity of its XPB and XPD subunits, thereby facilitating the recruitment of downstream repair factors.

163

Publications

15.5K

Citations

678

Authors

229

Institutions

Publications per year

2017–2026

23

Parents

Publications

163

DNA Repair Helicase: a Component of BTF2 (TFIIH) Basic Transcription Factor

Laurent Schaeffer, Richard Roy, Sandrine Humbert et al. · Science · 1993 · 792 citations

, , +15

p53 modulation of TFIIH–associated nucleotide excision repair activity

Xin Wei Wang, Heidi Yeh, Laurent Schaeffer et al. · Nature Genetics · 1995 · 555 citations · Full text

, , +15

Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II

Ronny Drapkin, Joyce T. Reardon, Athar Ansari et al. · Nature · 1994 · 475 citations

, , +13

The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor

Richard Roy, J P Adamczewski, Thierry Seroz et al. · Cell · 1994 · 434 citations · Full text

, , +12

TFIIH is negatively regulated by cdk8-containing mediator complexes

Sasha Akoulitchev, Sergei Chuikov, Danny Reinberg · Nature · 2000 · 387 citations

, , +6

1–5 of 163

Authors

678

  1. JE
    Jean‐Marc Egly

    Inserm, France

    30 publications · 4.5K citations

    28

    h-index

  2. FC
    Frédéric Coin

    Institut de génétique et de biologie moléculaire et cellulaire, France

    19 publications · 2.8K citations

    18

    h-index

  3. JH
    Jan H.J. Hoeijmakers

    Erasmus University Rotterdam, Netherlands

    15 publications · 3.2K citations

    15

    h-index

  4. WV
    Wim Vermeulen

    Erasmus MC, Netherlands

    16 publications · 2.8K citations

    15

    h-index

  5. JE
    Jean‐Marc Egly

    Centre National de la Recherche Scientifique, France

    12 publications · 1.7K citations

    12

    h-index

1–5 of 678

Institutions

229

  1. Inserm

    Paris, France

    35 h-index

    150 publications

    22.2K citations

  2. Institut de génétique et de biologie moléculaire et cellulaire

    Illkirch-Graffenstaden, France

    34 h-index

    146 publications

    18.1K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    32 h-index

    136 publications

    19K citations

  4. Erasmus University Rotterdam

    Rotterdam, The Netherlands

    17 h-index

    91 publications

    9.2K citations

  5. Erasmus MC

    Rotterdam, The Netherlands

    17 h-index

    86 publications

    11.1K citations

  6. National Cancer Institute

    Bethesda, United States

    10 h-index

    34 publications

    5.6K citations

  7. Howard Hughes Medical Institute

    Chevy Chase, United States

    10 h-index

    22 publications

    3.6K citations

  8. National Institutes of Health

    Bethesda, United States

    9 h-index

    28 publications

    6.4K citations

1–8 of 229

Venues

  1. Journal of Biological Chemistry

    JBC · 23 publications · 1.8K citations

    20

    h-index

  2. Molecular Cell

    14 publications · 2.1K citations

    14

    h-index

  3. Nucleic Acids Research

    12 publications · 505 citations

    12

    h-index

  4. Molecular and Cellular Biology

    MCB · 9 publications · 563 citations

    9

    h-index

  5. Cell

    8 publications · 1.3K citations

    8

    h-index

1–5