Concepedia

Telomeric Silencing

Telomeric Silencing is a form of transcriptional silencing that occurs when gene expression is repressed in genomic regions adjacent to telomeres due to the spread of heterochromatin and the action of silencing factors such as Sir proteins, distinguishing it from silencing mechanisms at other chromosomal loci.

216

Publications

24.3K

Citations

782

Authors

271

Institutions

Publications per year

2017–2026

14

Parents

Publications

216

<i>TLC1</i> : Template RNA Component of <i>Saccharomyces cerevisiae</i> Telomerase

Miriam Singer, Daniel E. Gottschling · Science · 1994 · 735 citations

, , +17

A phylogenetically conserved NAD <sup>+</sup> -dependent protein deacetylase activity in the Sir2 protein family

Jeffrey S. Smith, Carrie Baker Brachmann, Ivana Celic et al. · Proceedings of the National Academy of Sciences · 2000 · 722 citations

, , +16

SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast.

Sabine Strahl‐Bolsinger, Andreas Hecht, Kang Luo et al. · Genes & Development · 1997 · 670 citations · Full text

, , +17

Components of the Ku‐dependent non‐homologous end‐joining pathway are involved in telomeric length maintenance and telomeric silencing

Simon J. Boulton · The EMBO Journal · 1998 · 636 citations · Full text

, , +13

The Mammalian SIR2α Protein Has a Role in Embryogenesis and Gametogenesis

Michael W. McBurney, Xiaofeng Yang, Karen Jardine et al. · Molecular and Cellular Biology · 2002 · 618 citations · Full text

, , +12

1–5 of 216

Authors

782

  1. LP
    Lorraine Pillus

    University of California San Diego, United States

    11 publications · 1.2K citations

    11

    h-index

  2. DS
    David Shore

    University of Geneva, Switzerland

    10 publications · 1.5K citations

    10

    h-index

  3. DE
    Daniel E. Gottschling

    Fred Hutch Cancer Center, United States

    9 publications · 2.4K citations

    9

    h-index

  4. SM
    Susan M. Gasser

    Friedrich Miescher Institute, Switzerland

    8 publications · 1.4K citations

    8

    h-index

  5. AJ
    Arthur J. Lustig

    Tulane University, United States

    8 publications · 734 citations

    8

    h-index

1–5 of 782

Institutions

271

  1. University of California San Diego

    San Diego, United States

    11 h-index

    25 publications

    906 citations

  2. Harvard University

    Cambridge, United States

    10 h-index

    28 publications

    6.7K citations

  3. Cornell University

    Ithaca, United States

    9 h-index

    21 publications

    1.4K citations

  4. Fred Hutch Cancer Center

    Seattle, United States

    9 h-index

    31 publications

    5.6K citations

  5. University of California, Berkeley

    Berkeley, United States

    8 h-index

    17 publications

    2.8K citations

  6. University of Geneva

    Geneva, Switzerland

    7 h-index

    19 publications

    1.8K citations

  7. Stony Brook University

    Stony Brook, United States

    6 h-index

    15 publications

    2.1K citations

  8. Johns Hopkins University

    Baltimore, United States

    6 h-index

    27 publications

    12.1K citations

1–8 of 271

Venues

  1. Molecular and Cellular Biology

    MCB · 33 publications · 3.5K citations

    27

    h-index

  2. Genetics

    37 publications · 2.2K citations

    26

    h-index

  3. Genes & Development

    19 publications · 4.9K citations

    19

    h-index

  4. Journal of Biological Chemistry

    JBC · 16 publications · 1.9K citations

    14

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 10 publications · 1.8K citations

    10

    h-index

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