Concepedia

Targeted Therapy Evaluation

Targeted Therapy Evaluation is a systematic research framework within oncological preclinical modeling that assesses the efficacy, specificity, and biological impact of molecularly guided interventions in spontaneous animal cancer models to determine their therapeutic potential and mechanistic relevance.

239

Publications

11.8K

Citations

2.4K

Authors

830

Institutions

Publications per year

2017–2026

120

Parents

Publications

239

Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial

Christophe Le Tourneau, Jean-Pierre Delord, Anthony Gonçalvès et al. · The Lancet Oncology · 2015 · 1.1K citations

, , +14

Analyses of repeated failures in cancer therapy for solid tumors: poor tumor‐selective drug delivery, low therapeutic efficacy and unsustainable costs

Hiroshi Maeda, Mahin Khatami · Clinical and Translational Medicine · 2018 · 486 citations · Full text

, , +16

Translating cancer research into targeted therapeutics

Johann S. de Bono, Alan Ashworth · Nature · 2010 · 338 citations

, , +12

Molecular Landscape and Actionable Alterations in a Genomically Guided Cancer Clinical Trial: National Cancer Institute Molecular Analysis for Therapy Choice (NCI-MATCH)

Keith T. Flaherty, Robert J. Gray, Alice P. Chen et al. · Journal of Clinical Oncology · 2020 · 295 citations · Full text

, , +17

Immunoscintigraphic detection of the ED-B domain of fibronectin, a marker of angiogenesis, in patients with cancer.

Monica Santimaria, G Moscatelli, Giuseppe Viale et al. · PubMed · 2003 · 294 citations

, , +15

1–5 of 239

Authors

2.4K

  1. RK
    Razelle Kurzrock

    The University of Texas MD Anderson Cancer Center, United States

    7 publications · 553 citations

    7

    h-index

  2. KT
    Keith T. Flaherty

    Massachusetts General Hospital, United States

    6 publications · 401 citations

    6

    h-index

  3. DS
    David S. Hong

    The University of Texas MD Anderson Cancer Center, United States

    6 publications · 522 citations

    6

    h-index

  4. JJ
    Jennifer J. Wheler

    The University of Texas MD Anderson Cancer Center, United States

    5 publications · 492 citations

    5

    h-index

  5. AM
    Apostolia M. Tsimberidou

    The University of Texas MD Anderson Cancer Center, United States

    5 publications · 492 citations

    5

    h-index

1–5 of 2.4K

Institutions

830

  1. The University of Texas MD Anderson Cancer Center

    Houston, United States

    24 h-index

    125 publications

    7.1K citations

  2. Dana-Farber Cancer Institute

    Boston, United States

    18 h-index

    65 publications

    4.8K citations

  3. Massachusetts General Hospital

    Boston, United States

    14 h-index

    47 publications

    2.3K citations

  4. Memorial Sloan Kettering Cancer Center

    New York, United States

    13 h-index

    77 publications

    2.6K citations

  5. National Cancer Institute

    Bethesda, United States

    12 h-index

    43 publications

    4.8K citations

  6. Harvard University

    Cambridge, United States

    11 h-index

    45 publications

    2.8K citations

  7. Sarah Cannon

    Nashville, United States

    10 h-index

    31 publications

    720 citations

  8. Institut Gustave Roussy

    Villejuif, France

    9 h-index

    31 publications

    1.3K citations

1–8 of 830

Venues

  1. Journal of Clinical Oncology

    61 publications · 2.2K citations

    28

    h-index

  2. Clinical Cancer Research

    11 publications · 762 citations

    11

    h-index

  3. Oncotarget

    9 publications · 374 citations

    9

    h-index

  4. Journal of Nuclear Medicine

    7 publications · 287 citations

    7

    h-index

  5. Annals of Oncology

    6 publications · 331 citations

    6

    h-index

1–5