Concepedia

Targeted Gene Knockout

Targeted Gene Knockout is a genome editing technique that belongs to the class of genetic manipulation methods, distinguished by its precise disruption of a specific gene sequence through directed DNA double-strand breaks, thereby abolishing the gene’s function in a controlled and intentional manner.

171

Publications

15.5K

Citations

1.2K

Authors

425

Institutions

Publications per year

2017–2026

45

Parents

Publications

171

Effective targeted gene ‘knockdown’ in zebrafish

Aidas Nasevicius, Stephen C. Ekker · Nature Genetics · 2000 · 2.5K citations

, , +10

Demonstration of CRISPR/Cas9/sgRNA-mediated targeted gene modification in Arabidopsis, tobacco, sorghum and rice

Wenzhi Jiang, Huanbin Zhou, Honghao Bi et al. · Nucleic Acids Research · 2013 · 1.3K citations · Full text

, , +16

Exported Proteins Required for Virulence and Rigidity of Plasmodium falciparum-Infected Human Erythrocytes

Alexander G. Maier, Melanie Rug, Matthew T. O’Neill et al. · Cell · 2008 · 532 citations · Full text

, , +17

A Rapid Method for Directed Gene Knockout for Screening in G0 Zebrafish

Roland S. Wu, Ian I. Lam, Hilary Clay et al. · Developmental Cell · 2018 · 449 citations · Full text

, , +14

Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes

Ting Li, Sheng Huang, Xuefeng Zhao et al. · Nucleic Acids Research · 2011 · 415 citations · Full text

, , +13

1–5 of 171

Authors

1.2K

  1. BY
    Bing Yang

    Iowa State University, United States

    3 publications · 1.8K citations

    3

    h-index

  2. DP
    Donald P. Weeks

    University of Nebraska–Lincoln, United States

    3 publications · 1.8K citations

    3

    h-index

  3. PP
    Peter P. Liu

    University of Toronto, Canada

    2 publications · 195 citations

    2

    h-index

  4. MP
    Martin Petric

    BC Centre for Disease Control, Canada

    2 publications · 195 citations

    2

    h-index

  5. EP
    Eric P. Rahrmann

    University of Minnesota, United States

    2 publications · 72 citations

    2

    h-index

1–5 of 1.2K

Institutions

425

  1. Harvard University

    Cambridge, United States

    5 h-index

    6 publications

    272 citations

  2. Chinese Academy of Sciences

    Beijing, China

    5 h-index

    39 publications

    7.3K citations

  3. University of Toronto

    Toronto, Canada

    5 h-index

    21 publications

    1.8K citations

  4. National Institutes of Health

    Bethesda, United States

    5 h-index

    16 publications

    2.3K citations

  5. Cornell University

    Ithaca, United States

    4 h-index

    17 publications

    1.5K citations

  6. Heidelberg University

    Heidelberg, Germany

    4 h-index

    8 publications

    1.4K citations

  7. The University of Melbourne

    Melbourne, Australia

    4 h-index

    21 publications

    1.4K citations

  8. Hiroshima University

    Hiroshima, Japan

    4 h-index

    9 publications

    567 citations

1–8 of 425

Venues

  1. PLoS ONE

    9 publications · 662 citations

    9

    h-index

  2. Nucleic Acids Research

    8 publications · 2.2K citations

    8

    h-index

  3. The Journal of Immunology

    JI · 7 publications · 690 citations

    7

    h-index

  4. Scientific Reports

    5 publications · 222 citations

    5

    h-index

  5. Genetics

    4 publications · 336 citations

    4

    h-index

1–5