Talin Function is a molecular mechanism that mediates the mechanical linkage between integrin receptors and the actin cytoskeleton by allosterically activating integrins and modulating focal adhesion dynamics.
306
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26.1K
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1.3K
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383
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Publications per year
2017–2026
60
Parents
Publications
306
Calpain-mediated proteolysis of talin regulates adhesion dynamics
Santos J. Franco, Mary A. Rodgers, Benjamin J. Perrin et al. · Nature Cell Biology · 2004 · 553 citations
Two-piconewton slip bond between fibronectin and the cytoskeleton depends on talin
Guoying Jiang, Grégory Giannone, David R. Critchley et al. · Nature · 2003 · 443 citations
1–5 of 306
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15
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1–5 of 1.3K
Institutions
383
University of Leicester
Leicester, United Kingdom
45 h-index
202 publications
23.1K citations
University of California San Diego
San Diego, United States
27 h-index
100 publications
11.7K citations
Technical University of Munich
Munich, Germany
15 h-index
35 publications
3.4K citations
University of North Carolina at Chapel Hill
Chapel Hill, United States
13 h-index
35 publications
2.8K citations
University of Kent
Canterbury, United Kingdom
13 h-index
29 publications
2K citations
Yale University
New Haven, United States
12 h-index
48 publications
9.8K citations
Columbia University
New York, United States
11 h-index
34 publications
5.7K citations
Max Planck Institute of Biochemistry
Martinsried, Germany
11 h-index
45 publications
8.5K citations
1–8 of 383
Venues
- Journal of Biological Chemistry
JBC · 29 publications · 2.8K citations
25
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- The Journal of Cell Biology
JCB · 26 publications · 3.5K citations
23
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- Journal of Cell Science
16 publications · 1K citations
16
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- Proceedings of the National Academy of Sciences
PNAS · 12 publications · 1.4K citations
12
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- Molecular Biology of the Cell
MBC · 12 publications · 1.1K citations
12
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