Concepedia

Tacr3 Mutations

TACR3 Mutations is a genetic alteration in the tachykinin receptor 3 gene that disrupts neurokinin B signaling and is specifically associated with normosmic idiopathic hypogonadotropic hypogonadism, a disorder impairing the initiation or progression of puberty.

24

Publications

2.9K

Citations

196

Authors

88

Institutions

Publications per year

2017–2026

2

Parents

Publications

24

TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction

A. Kemal Topaloğlu, Frank Reimann, Metin Güçlü et al. · Nature Genetics · 2008 · 956 citations · Full text

, , +17

Inactivating<i>KISS1</i>Mutation and Hypogonadotropic Hypogonadism

A. Kemal Topaloğlu, Javier A. Tello, Leman Damla Kotan et al. · New England Journal of Medicine · 2012 · 468 citations · Full text

, , +17

TAC3/TACR3 Mutations Reveal Preferential Activation of Gonadotropin-Releasing Hormone Release by Neurokinin B in Neonatal Life Followed by Reversal in Adulthood

Elena Gianetti, Cíntia Tusset, Sekoni D. Noel et al. · The Journal of Clinical Endocrinology & Metabolism · 2010 · 288 citations · Full text

, , +14

<i>TAC3</i>and<i>TACR3</i>Defects Cause Hypothalamic Congenital Hypogonadotropic Hypogonadism in Humans

Jacques Young, Jérôme Bouligand, Bruno Francou et al. · The Journal of Clinical Endocrinology & Metabolism · 2010 · 245 citations · Full text

, , +17

Hypogonadotropic Hypogonadism due to a Novel Missense Mutation in the First Extracellular Loop of the Neurokinin B Receptor

Tülay Güran, Gwen Tolhurst, Abdullah Bereket et al. · The Journal of Clinical Endocrinology & Metabolism · 2009 · 135 citations · Full text

, , +15

1–5 of 24

Authors

196

  1. AK
    A. Kemal Topaloğlu

    Cukurova University, Türkiye

    4 publications · 1.6K citations

    4

    h-index

  2. LD
    Leman Damla Kotan

    Cukurova University, Türkiye

    4 publications · 1.6K citations

    4

    h-index

  3. SB
    Stephanie B. Seminara

    Massachusetts General Hospital, United States

    4 publications · 490 citations

    4

    h-index

  4. CT
    Cíntia Tusset

    Universidade de São Paulo, Brazil

    3 publications · 365 citations

    3

    h-index

  5. BY
    Bilgin Yüksel

    Cukurova University, Türkiye

    3 publications · 1.5K citations

    3

    h-index

1–5 of 196

Institutions

88

  1. Cukurova University

    Adana, Türkiye

    4 h-index

    24 publications

    9.3K citations

  2. Massachusetts General Hospital

    Boston, United States

    4 h-index

    14 publications

    2.6K citations

  3. Universidade de São Paulo

    São Paulo, Brazil

    3 h-index

    12 publications

    839 citations

  4. Brigham and Women's Hospital

    Boston, United States

    3 h-index

    13 publications

    1.4K citations

  5. Inserm

    Paris, France

    3 h-index

    22 publications

    3.6K citations

  6. Université Paris Cité

    Paris, France

    2 h-index

    3 publications

    507 citations

  7. University of Cambridge

    Cambridge, United Kingdom

    2 h-index

    12 publications

    5.7K citations

  8. Assistance Publique – Hôpitaux de Paris

    Paris, France

    2 h-index

    11 publications

    1.8K citations

1–8 of 88

Venues

  1. The Journal of Clinical Endocrinology & Metabolism

    JCEM · 3 publications · 668 citations

    3

    h-index

  2. PLoS ONE

    2 publications · 122 citations

    2

    h-index

  3. Endocrinology

    2 publications · 181 citations

    2

    h-index

  4. 2

    h-index

  5. Hormone Research in Paediatrics

    2 publications · 36 citations

    2

    h-index

1–5