Concepedia

Systems-level Functional Annotation

Systems-Level Functional Annotation is a systematic approach to functional genomics that integrates diverse biological data types across molecular, cellular, and organismal scales to infer the functional roles of genes and proteins within the context of complex biological systems, distinguishing it from gene- or pathway-centric annotation methods by emphasizing emergent properties and network-level interactions.

16

Publications

17.1K

Citations

186

Authors

70

Institutions

Publications per year

2017–2026

5

Parents

Publications

16

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

Yingyao Zhou, Bin Zhou, Lars Pache et al. · Nature Communications · 2019 · 15.6K citations · Full text

, , +10

A Genome-Scale Resource for In Vivo Tag-Based Protein Function Exploration in C. elegans

Mihail Sarov, John I. Murray, Kristin Schanze et al. · Cell · 2012 · 295 citations · Full text

, , +15

BABELOMICS: a systems biology perspective in the functional annotation of genome-scale experiments

Fátima Al‐Shahrour, Pablo Mínguez, Joaquín Tárraga et al. · Nucleic Acids Research · 2006 · 269 citations · Full text

, , +16

Discovery of uncharacterized cellular systems by genome-wide analysis of functional linkages

Shailesh V. Date, Edward M. Marcotte · Nature Biotechnology · 2003 · 234 citations

, , +8

An integrative ENCODE resource for cancer genomics

Jing Zhang, Donghoon Lee, Vineet K. Dhiman et al. · Nature Communications · 2020 · 185 citations · Full text

, , +17

1–5 of 16

Authors

186

  1. MS
    M Snyder

    Stanford University, United States

    3 publications · 495 citations

    3

    h-index

  2. JC
    Juan Carlos Rivera‐Mulia

    Florida State University, United States

    2 publications · 200 citations

    2

    h-index

  3. DM
    David M. Gilbert

    Florida State University, United States

    2 publications · 200 citations

    2

    h-index

  4. PJ
    Peng Jiang

    Dana-Farber Cancer Institute, United States

    2 publications · 200 citations

    2

    h-index

  5. SK
    Sumit K. Chanda

    Sanford Burnham Prebys Medical Discovery Institute, United States

    2 publications · 15.8K citations

    2

    h-index

1–5 of 186

Institutions

70

  1. Yale University

    New Haven, United States

    4 h-index

    58 publications

    6.1K citations

  2. Stanford University

    Stanford, United States

    4 h-index

    9 publications

    1.6K citations

  3. University of Chicago

    Chicago, United States

    2 h-index

    14 publications

    1.4K citations

  4. Dartmouth College

    Hanover, United States

    2 h-index

    4 publications

    400 citations

  5. Genomics Institute of the Novartis Research Foundation

    San Diego, United States

    2 h-index

    9 publications

    63.3K citations

  6. Chinese University of Hong Kong

    Hong Kong, Hong Kong

    2 h-index

    4 publications

    400 citations

  7. University of California San Diego

    San Diego, United States

    2 h-index

    8 publications

    31.4K citations

  8. Florida State University

    Tallahassee, United States

    2 h-index

    9 publications

    985 citations

1–8 of 70

Venues

  1. PLoS ONE

    2 publications · 51 citations

    2

    h-index

  2. Nature Chemical Biology

    2 publications · 268 citations

    2

    h-index

  3. Nature Communications

    2 publications · 15.8K citations

    2

    h-index

  4. Neural Computing and Applications

    1 publications · 16 citations

    1

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 1 publications · 35 citations

    1

    h-index

1–5