Concepedia

Synucleinopathy Models

Synucleinopathy Models is a class of neurological disease models that specifically recapitulate the pathological accumulation of misfolded alpha-synuclein protein in neurons, thereby enabling the study of neurodegenerative disorders such as Parkinson’s disease, dementia with Lewy bodies, and multiple system atrophy.

616

Publications

54.1K

Citations

3.8K

Authors

972

Institutions

Publications per year

2017–2026

309

Parents

Publications

616

Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson’s Disease

Sangjune Kim, Seung‐Hwan Kwon, Tae‐In Kam et al. · Neuron · 2019 · 1.4K citations · Full text

, , +16

Neuronal α-Synucleinopathy with Severe Movement Disorder in Mice Expressing A53T Human α-Synuclein

Benoit I. Giasson, John E. Duda, Shawn M. Quinn et al. · Neuron · 2002 · 1.3K citations · Full text

, , +14

Exogenous α-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells

Kelvin C. Luk, Cheng Song, Patrick O’Brien et al. · Proceedings of the National Academy of Sciences · 2009 · 993 citations · Full text

, , +17

Prion-like spreading of pathological α-synuclein in brain

Masami Masuda‐Suzukake, Takashi Nonaka, Masato Hosokawa et al. · Brain · 2013 · 888 citations · Full text

, , +17

Human α-synuclein-harboring familial Parkinson's disease-linked Ala-53 → Thr mutation causes neurodegenerative disease with α-synuclein aggregation in transgenic mice

Michael K. Lee, Wanda L.H. Stirling, Yanqun Xu et al. · Proceedings of the National Academy of Sciences · 2002 · 840 citations · Full text

, , +17

1–5 of 616

Authors

3.8K

  1. EM
    Eliezer Masliah

    University of California San Diego, United States

    63 publications · 9.1K citations

    46

    h-index

  2. ER
    Edward Rockenstein

    University of California San Diego, United States

    41 publications · 6.5K citations

    37

    h-index

  3. AA
    Anthony Adame

    University of California San Diego, United States

    27 publications · 4.2K citations

    26

    h-index

  4. KC
    Kelvin C. Luk

    University of Pennsylvania, United States

    25 publications · 3.5K citations

    22

    h-index

  5. MM
    Michael Mante

    University of California San Diego, United States

    20 publications · 2K citations

    19

    h-index

1–5 of 3.8K

Institutions

972

  1. University of California San Diego

    San Diego, United States

    49 h-index

    316 publications

    44.5K citations

  2. University of Pennsylvania

    Philadelphia, United States

    30 h-index

    122 publications

    27.3K citations

  3. Harvard University

    Cambridge, United States

    23 h-index

    94 publications

    9.1K citations

  4. Johns Hopkins University

    Baltimore, United States

    20 h-index

    142 publications

    55.4K citations

  5. Lund University

    Lund, Sweden

    19 h-index

    75 publications

    4K citations

  6. University of Florida

    Gainesville, United States

    19 h-index

    100 publications

    12.7K citations

  7. Massachusetts General Hospital

    Boston, United States

    17 h-index

    59 publications

    10.2K citations

  8. Johns Hopkins Medicine

    Baltimore, United States

    17 h-index

    117 publications

    41.7K citations

1–8 of 972

Venues

  1. Neurobiology of Disease

    35 publications · 2.9K citations

    27

    h-index

  2. Journal of Neuroscience

    24 publications · 4.8K citations

    24

    h-index

  3. PLoS ONE

    25 publications · 2.1K citations

    21

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 20 publications · 6.9K citations

    20

    h-index

  5. Acta Neuropathologica Communications

    21 publications · 1.4K citations

    20

    h-index

1–5